Stemona sessilifolia, S. japonica and S. tuberosa are the three genuine sources of Stemonae Radix specified in the Chinese Pharmacopoeia (CP) for antitussive and insecticidal remedy. Significant variations in alkaloids composition and content, as well as different degree of antitussive activity were found among them. In order to accurately identify the genuine sources of Stemonae Radix in the g...

nigella sativa (n. sativa), which belongs to the botanical family of ranunculaceae, is a widely used medicinal plant all over the world. n. sativa seeds and oil have been used in the treatment of different diseases. various studies on n. sativa have been carried out and a broad spectrum of its pharmacological actions have been established which include antioxidant, antidiabetic, anticancer, ant...

Dextromethorphan (DM) is a noncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist, which is widely used as an antitussive agent. DM also prevents neuronal damage and modulates pain sensation via noncompetitive antagonism of excitatory amino acids (EAAs). DM has been found to be useful in the treatment of pain in cancer patients and in the treatment of methotrexate-induced neurotoxicity....

Several therapeutic effects including hypnotic, antispasmodic, treatment of abdominal and chest pain and strengthening the heart have been described for the flowers of Rosa damascena. North American Indian tribes use a decoction of the roots obtained from the Rosa damascena plant as a cough remedy and to treat eye problem. Therefore, in the present study the antitussive effect of this plant in ...

Nigella sativa (N. sativa), which belongs to the botanical family of Ranunculaceae, is a widely used medicinal plant all over the world. N. sativa seeds and oil have been used in the treatment of different diseases. Various studies on N. sativa have been carried out and a broad spectrum of its pharmacological actions have been established which include antioxidant, antidiabetic, anticancer, ant...

We have previously found that dextromethorphan (DM), over-the-counter cough suppressant, impairs memory retention in water maze task, when it is repeatedly administrated to adolescent female rats at high doses. In this study we examined first if ovariectomy ameliorates the DM-induced memory impairment in female rats, and then whether or not the DM effect is revived by estrogen replacement in ov...

BACKGROUND Upper respiratory tract infections (URTI) are common. The etiologic factor is usually viral, but many physicians prescribe antibiotics. We aimed to evaluate parents' expectations of and knowledge about the role of antibiotics in childhood URTI. METHODS The study was conducted in thirteen primary care pediatric clinics. Parents of children aged 3 months to 6 years who attended with ...

Fever uncontrolled by paracetamol is a common and disturbing issue to many parents. Current evidence does not show any significant benefit from sponging which on the contrary may cause discomfort to the child [1]. Similarly, simple febrile convulsions do not require routine administration of anticonvulsants. Cough remedies in the form of variously concocted antitussives and mucolytics are no be...