نتایج جستجو برای: as replacers for ctc

تعداد نتایج: 11760579  

2016
Takeshi Sawada Jungo Araki Toshinari Yamashita Manami Masubuchi Tsuneko Chiyoda Mayu Yunokawa Kumiko Hoshi Shoichi Tao Shohei Yamamura Shouki Yatsushiro Kaori Abe Masatoshi Kataoka Tatsu Shimoyama Yoshiharu Maeda Katsumasa Kuroi Kenji Tamura Tsuneo Sawazumi Hironobu Minami Yoshihiko Suda Fumiaki Koizumi

Various types of circulating tumor cell (CTC) detection systems have recently been developed that show a high CTC detection rate. However, it is a big challenge to find a system that can provide better prognostic value than CellSearch in head-to-head comparison. We have developed a novel semi-automated CTC enumeration system (fluidic cell microarray chip system, FCMC) that captures CTC independ...

2015
Monika Vishnoi Sirisha Peddibhotla Wei Yin Antonio T. Scamardo Goldy C. George David S. Hong Dario Marchetti

Uncovering CTCs phenotypes offer the promise to dissect their heterogeneity related to metastatic competence. CTC survival rates are highly variable and this can lead to many questions as yet unexplored properties of CTCs responsible for invasion and metastasis vs dormancy. We isolated CTC subsets from peripheral blood of patients diagnosed with or without breast cancer brain metastasis. CTC su...

2014
B. A. S. Jaeger J. Jueckstock U. Andergassen J. Salmen F. Schochter V. Fink M. Alunni-Fabbroni M. Rezai Th. Beck M. W. Beckmann K. Friese T. W. P. Friedl W. Janni B. Rack

BACKGROUND Evidence is accumulating that circulating tumor cells (CTC) out of peripheral blood can serve as prognostic marker not only in metastatic but also in early breast cancer (BC). Various methods are available to detect CTC. Comparisons between the different techniques, however, are rare. MATERIAL AND METHODS We evaluate two different methods for CTC enrichment and detection in primary...

2005
Thomas D. Coates Martine Torres Jon Harman Vicki Williams

Chlorotetracycline (CTC) has been used in many cells as a probe for membranous calcium. In polymorphonuclear neutrophils (PMN). the changes in CTC fluorescence upon stimulation are considered to monitor an early event in the activation process. Using quantitative video-enhanced microscopy. we report that in resting cells about 80% of the CTC signal emanates from the perinuclear region of the ce...

Journal: :The Journal of investigative dermatology 2010
Vincenzo De Giorgi Pamela Pinzani Francesca Salvianti John Panelos Milena Paglierani Agata Janowska Marta Grazzini Janine Wechsler Claudio Orlando Marco Santucci Torello Lotti Mario Pazzagli Daniela Massi

Analysis of circulating tumor cells (CTC) in the peripheral blood of cutaneous melanoma patients provides information on the metastatic process and potentially improves patient management. The isolation by size of epithelial tumor cells (ISET) is a direct method for CTC identification in which tumor cells are collected by filtration as a result of their large size. So far, ISET has been applied...

2016
David Lorente David Olmos Joaquin Mateo Diletta Bianchini George Seed Martin Fleisher Daniel C. Danila Penny Flohr Mateus Crespo Ines Figueiredo Susana Miranda Kurt Baeten Arturo Molina Thian Kheoh Robert McCormack Leon W.M.M. Terstappen Howard I. Scher Johann S. de Bono

BACKGROUND Treatment response biomarkers are urgently needed for castration-resistant prostate cancer (CRPC). Baseline and post-treatment circulating tumor cell (CTC) counts of ≥5 cells/7.5ml are associated with poor CRPC outcome. OBJECTIVE To determine the value of a ≥30% CTC decline as a treatment response indicator. DESIGN, SETTING, AND PARTICIPANTS We identified patients with a baseline...

پایان نامه :0 1374

the following null hypothesis was proposed: h : there is no significant difference between the use of semantically or communicatively translates scientific texts. to test the null hypothesis, a number of procedures were taken first, two passages were selected form soyrcebooks of food and nutrition industry and gardening deciplines. each, in turn, was following by a number of comprehension quest...

Journal: :Annals of oncology : official journal of the European Society for Medical Oncology 2010
F-C Bidard C Mathiot S Delaloge E Brain S Giachetti P de Cremoux M Marty J-Y Pierga

BACKGROUND Circulation of cancer cells in the blood is a mandatory step for metastasis, but circulating tumor cells (CTC) have a low metastatic efficiency in preclinical animal models. In this prospective study, we reported the clinical outcome of nonmetastatic breast cancer patients according to CTC detection. PATIENTS AND METHODS In 115 nonmetastatic patients diagnosed with large operable o...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه صنعتی اصفهان - دانشکده منابع طبیعی 1392

nowadays, air pollution is a global problem that has had significant growth by technology development, population growth andindustrial development. industrial development brought natural resources deterioration, more manufacturing products, and more environmental pollutants. if pollutant won’t be controlled, human-being and wildlife will face the critical risks. significant release and critical...

2011
Zhenxing Chi Rutao Liu Hongxu Yang Hengmei Shen Jing Wang

Tetracycline (TC) and chlortetracycline (CTC) are common members of the widely used veterinary drug tetracyclines, the residue of which in the environment can enter human body, being potentially harmful. In this study, we establish a new strategy to probe the binding modes of TC and CTC with trypsin based on spectroscopic and computational modeling methods. Both TC and CTC can interact with try...

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