Detection of low frequency single nucleotide polymorphisms (SNPs) has important implications in early screening for tumorgenesis, genetic disorders and pathogen drug resistance. Nucleic acid arrays are a powerful tool for genome-scale SNP analysis, but detection of low-frequency SNPs in a mixed population on an array is problematic. We demonstrate a model assay for HIV-1 drug resistance mutatio...

There are three objectives to the present work. First, starting from a boundary element (BE) formulation of low Reynolds number hydrodynamics, model the translational diffusion of macromolecules modeled as an array of non-overlapping beads, and show how this approach is equivalent to previous formulations of "bead hydrodynamics" and under what conditions. Second, show how this approach can be i...

Gas tungsten arc welding (GTAW) is important in those manufacturing where it significant to control the mechanical and metallurgical characteristics its weld bead geometry. This work has been committed study influence of oxide fluxes on 4 mm thick 304 austenitic stainless steel plates. The Al2O3 TiO2 were used as an flux powder form are mixed with acetone. prepared mixture applied plate without...

The dynamics of fluid-borne superparamagnetic bead transport by field-driven domain walls (DWs) in submicrometer ferromagnetic tracks is studied experimentally together with numerical and analytical modeling. A combination of micromagnetic modeling and numerical calculation is used to determine the strength of bead-DW interaction for a range of track geometries and bead sizes. The maximum DW ve...

In the present study, textural and structural characterizations of chitosan bead for immobilization of alpha amylase were studied in detail by N2 adsorption–desorption, Microspore Analysis (MP), Barrett–Joyner–Halenda (BJH) plots and Field Emission Scanning Electron Microscope (FESEM) observations. Pore structure observation revealed chemical activation of chitosan bead by glutaralde...

Additive Manufacturing describes the technologies that can produce a physical model out of a computer model with a layer-by-layer production process. Additive Manufacturing technologies, as compared to traditional manufacturing methods, have the high capability of manufacturing the complex components using minimum energy and minimum consumption. These technologies have brought about the possibi...