Metabolic engineering has developed microbial cell factories that can convert renewable carbon sources into biofuels. Current molecular biology tools can efficiently alter enzyme levels to redirect carbon fluxes toward biofuel production, but low product yield and titer in large bioreactors prevent the fulfillment of cheap biofuels. There are three major roadblocks preventing economical biofuel...

The importance of supply chains in pharmacological industry is remarkable so that nowadays many pharmacological supply chains have an effective and critical role for supplying and distributing drugs in health area. So, this study studies a three-echelon pharmacological supply chain contained multi-distributor of raw materials, a pharmaceutical factory, and multi-drug distributors companies such...

This study investigates the optimal supply chain design for commodity chemicals (BTX, etc.) production via woody biomass fast pyrolysis and hydroprocessing pathway. The locations and capacities of distributed preprocessing hubs and integrated biorefinery facilities are optimized with a mixed integer linear programming model. In this integrated supply chain system, decisions on the biomass chipp...

The world seems to be raising its energy needs owing to an expanding population and people’s desire for higher living standards. Diversification biofuel sources have become an important energy issue in recent times. Among the various resources, algal biomass has received much attention in the recent years due to its relatively high growth rate, its vast potential to reduce greenhouse gas (GHG) ...

Modern manufacturing enterprises are required to collaborate by their business partners through their business process operations such as design, manufacture, distribution, and aftersales services. And furthermore performance evaluation is of great importance for effective supply chain man agement. Therefore, DEA can help companies to remove some of the in efficiencies in operational processes ...

in today’s competitive business environment, the design and management of supply chainnetwork is one of the most important challenges that managers encounter. the supply chain network shouldbe designed for satisfying of customer demands as well as minizing the total system costs. this paper presentsa multi-period multi-stage supply chain network design problem under demand uncertainty. the prob...

in this study, a cross-docking system is designed at strategic and tactical levels. for making the strategic decisions, a multi-objective nonlinear location allocation model for cross-docks is presented based on a distri-bution location allocation model by andreas klose and andreas drexl. the model is further developed to in-clude the whole supply chain members and the objective functions are w...

The size of the U.S. bioindustry will, to a large degree, be determined by the quantity and quality of biomass available. As the starting material in the biomass-to-biofuels supply chain, a sufficient and secure supply of affordable feedstocks is a critical step in accomplishing the Program goals. The Feedstock platform therefore relates strongly to all other facets of the program portfolio; it...

One of the most important points in a supply chain is customer-driven modeling, which reduces the bullwhip effect in the supply chain, as well as the costs of investment on the inventory and efficient transshipment of the products. Their homogeneity is reflected in the inventory-routing problem, which is a combination of distribution and inventory management. This paper considers a multi object...