proliferating pilomatricoma is a distinctive rare variant of pilomatricoma first described in 1997.very few cases of proliferating pilomatricoma have been reported in the literature until date. this report is a case of 65 years old male presenting with hard nodular lump on the right side of neck slowly increasing in size for the last 8 months. wide excision of the lump was performed with clear ...

The present study was conducted to investigate the effect of the diet containing Laurencia caspica (red algae) on blood parameters and digestive enzymes activity of goldfish after 90-day period. Goldfish (weight 6.10±0.1 gr) were divided to four experimental groups (30 individuals in each replication) including experimental treatment of the control group (without using red algae) and three trea...

objective: piwil2, a member of ago/piwi gene family containing piwi and paz domains, has been shown to be ectopically expressed in different cancer cells, especially its remarkable expression in cancer stem cells (cscs), and is also known to be essential for germ line stem cell self-renewal in various organisms. the hypothesis that csc may hold the key to the central problem of clinical oncolog...

introduction: human adipose-derived mesenchymal stem cells (hadscs) are easily accessible in the body, and under appropriate conditions, they can be directed toward various phenotypes. therefore, hadscs have been considered as a potential cell source for tissue engineering applications. hadscs are able to differentiate into endothelial cells which covers the interior surface of vessels, in vivo...

background: since embryonic stem (es) cells have the dual ability to proliferate indefinitely and differentiate into multiple tissue types, es cells could potentially provide an unlimited cell supply for human transplantation. objective: in order to study the differentiation of mouse embryonic stem (mes) cells, they were cultured in suspension by using es media without leukemia inhibitory facto...

background: epigenetic reprogramming of differentiated cells can modify somatic cells into pluripotential state. pluripotency can be induced in somatic cells by several approches. one of the easy ways to induce pluripotency is the exposure of the somatic cells to the embryonic stem cell (esc) extract. objective: the objective of this study was to increase the efficiency of reprogramming of gran...

Introduction: The Serum/Glucose deprivation -induced cell death in cultured PC12 cells represents a useful in vitro model for the study of brain ischemia and neurodegenerative disorders. Nigella sativa L. has been known as a source of antioxidants. To elucidate the neuroprotective actions of N. sativa extract in vitro, we studied the effect of N. sativa extract on cultured PC12 cells under s...

Introduction: Human adipose-derived mesenchymal stem cells (hADSCs) are easily accessible in the body, and under appropriate conditions, they can be directed toward various phenotypes. Therefore, hADSCs have been considered as a potential cell source for tissue engineering applications. hADSCs are able to differentiate into endothelial cells which covers the interior surface of vessels, in vi...