the aim of the present study was to develop exemestane loaded polymeric nanoparticles for improved oral bioavailability of exemestane. exemestane loaded nanoparticles were prepared by solvent displacement method with eudragit rl 100 and eudragit l 100 as polymers and pluronic® f-68 as surfactant. the influence of various formulation factors (drug: polymer ratio and concentration of surfactant) ...

INTRODUCTION In recent years, attention has been given to the development of abuse-deterrent and tamper-resistant opioid formulations in light of concern over the growing misuse and abuse of opioids prescribed for the treatment of chronic pain. AREAS COVERED This critical review discusses abuse-deterrent and tamper-resistant formulations, which may help to overcome concerns of misuse in using...

The aim of this study was to enhance the transdermal delivery of Sildenafil Citrate by encapsulation in nano sized ultra deformable vesicles, transfersomes. The thin film hydration and sonication technique was utilized in the preparation of Sildenafil Citrate loaded Transfersomes and both non ionic and ionic edge activators (anionic and cationic) were used in varying ratios to study their effec...

Compressive strength and splitting tensile strength are both mechanical properties of concrete that are utilized in structural design. This study presents gene expression programming (GEP) as a new tool for the formulations of splitting tensile strength from compressive strength of concrete. For purpose of building the GEP-based formulations, 536 experimental data have been gathered from existi...

Objective(s) The objective of this study was to prepare, characterize and evaluate the nanoliposomes containing safranal as a natural sunscreen and moisturizer factor. Materials and Methods The experimental formulations included homosalate reference, nanoliposomes containing 0.25, 0.5, 1, 2, 4 and 8% safranal and empty liposomes. The liposomes were prepared using fusion method and homogeniza...