نتایج جستجو برای: maternal serum screening test
تعداد نتایج: 1364594 فیلتر نتایج به سال:
Background and purpose: False positive in newborn hearing screening increases cost and maternal anxiety. We aimed to evaluate the effect of mode of delivery and screening age on false positive result of first screening test. Identifying and controlling these factors could reduce the rate of false positive tests. Materials and methods: In this study, 2784 infants were evaluated by otoacoustic...
The use of maternal serum screening to assess individual risk for Down’s syndrome is now standard in many countries and new techniques such as detailed ultrasound screening for nuchal translucency and DNA based tests are rapidly becoming available for mass screening. The increased uptake of these screening and diagnostic tests has provoked concerns about their potential impact on individuals an...
OBJECTIVE To demonstrate the potential value of screening for Down's Syndrome using highly correlated repeated measures of serum markers taken in the first and second trimesters of pregnancy. DESIGN A Monte Carlo simulation study. POPULATION Detection rates and false positive rates relating to the maternal age distribution of England and Wales for the period 1996 to 1998 were obtained using...
Preeclampsia and fetal growth restriction are major causes of perinatal mortality and morbidity. Several studies have shown that a generalized endothelial dysfunction is associated with these complications. Clinical trials have shown that pregnant women who demonstrate high resistance in uteroplacental blood flow are at higher risk for preeclampsia. Uterine artery Doppler studies both in the se...
BACKGROUND Intrauterine exposure to the metabolic alterations of maternal diabetes may increase the risk of later obesity. We determined whether offspring of mothers with diet-treated, gestational diabetes mellitus (GDM) have an increased risk of childhood obesity and examined the relationship between childhood obesity and metabolic markers of GDM. METHODS At a health maintenance organization...
OBJECTIVE To evaluate maternal serum C-reactive protein (CRP) concentrations in pregnancies complicated by preterm prelabor rupture of membranes (PPROM) in relation to the presence of microbial invasion of the amniotic cavity (MIAC) and/or intra-amniotic inflammation (IAI). METHODS Two hundred and eighty-seven women with singleton pregnancies complicated by PPROM between 2014 and 2016 were in...
INTRODUCTION To assess anxiety levels in mothers with low-risk pregnancies before and after offering routine serum screening. METHODS A prospective study was carried out at the Kandang Kerbau Women's and Children's Hospital in Singapore from February 2000 to August 2000. We used standard statistical analysis and Spielberger's state-trait anxiety inventory (STAI) which consists of 40 items to ...
OBJECTIVE To investigate the differences in costs and outcomes of Down syndrome screening using data from the First and Second Trimester Evaluation of Risk (FASTER) Trial. METHODS Seven possible screening options for Down syndrome were compared: 1) Triple Screen-maternal serum alpha fetoprotein, estriol, and hCG; 2) Quad-maternal serum alpha fetoprotein, estriol, hCG, and Inhibin A; 3) Combin...
OBJECTIVES To examine the effect of deviations in median nuchal translucency thickness (NT) and the spread in measurements on the performance of screening for trisomy 21 by maternal age and fetal NT, and by maternal age, fetal NT and maternal serum biochemistry. METHODS We simulated the NT and multiples of the median values for pregnancy-associated plasma protein-A (PAPP-A) and free beta-huma...
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