نتایج جستجو برای: mitochondrial gene

تعداد نتایج: 1242948  

Journal: :Diabetes 2007
Emmanuel Chevillotte Marta Giralt Bruno Miroux Daniel Ricquier Francesc Villarroya

Uncoupling protein-2 (UCP2) is a mitochondrial membrane transporter expressed in white adipose tissue. We observed that circulating adiponectin levels and adiponectin gene expression in adipose tissue are reduced in UCP2-null mice. We studied whether mitochondrial activity and its control by UCP2 may regulate adiponectin gene expression. In 3T3-L1 cells, increasing UCP2 mitochondrial levels by ...

2010
Miguel Gallach Chitra Chandrasekaran Esther Betrán

Gene duplication is probably the most important mechanism for generating new gene functions. However, gene duplication has been overlooked as a potentially effective way to resolve genetic conflicts. Here, we analyze the entire set of Drosophila melanogaster nuclearly encoded mitochondrial duplicate genes and show that both RNA- and DNA-mediated mitochondrial gene duplications exhibit an unexpe...

Entezari, Maliheh, Kazemi Asafeh, Farnoosh, Shirvani Shahenayati, Maryam,

Background: Q10 coenzyme is a potent antioxidant in the mitochondrial membrane. Releasing the oxygen free radicals occurs in the cerebral ischemia. Using Q10 coenzyme causes strength against oxidative after injury of cerebral ischemia during reperfusion. Also CoQ10 plays an important anti-apoptotic role to reduce Caspase 3 as a key enzyme neuroprotective in apoptosis. According to the sensitive...

Journal: :Wellcome open research 2023

We present a genome assembly from an individual Ypsolopha sequella (the Pied Smudge; Arthropoda; Insecta; Lepidoptera; Ypsolophidae). The sequence is 867 megabases in span. Most of the scaffolded into 30 chromosomal pseudomolecules with Z sex chromosome assembled. mitochondrial has also been assembled and 15.3 kilobases length. Gene annotation this on Ensembl ide...

Journal: :progress in biological sciences 2013
ahmad-reza katouzian hassan rajabi-maham

the identification of the efficiency of some mtdna genes of mus musculus species complex (house mouse) for biosystematics research was studied in this approach. recent studies have made use of different mitochondrial genes including nadh dehydrogenase genes, cytochrome b gene, cytochrome oxidase genes, d-loop region and whole mtdna genome to study the house mouse species. usage of each of these...

A Amirkhani P Parvizi,

Sergentomyia sintoni is the natural vector of Sauroleishmania species of lizards. This sandfly isabundance in and around the burrows of great gerbils. S. sintoni was collected from peridomestic animalshelters, inside and around houses and also from the nearby burrows of the gerbil reservoir hosts,Rhombomys opimus, in several provinces of Iran. Mitochondrial Cytochrome b (Cyt b) of sandflies, wh...

Journal: :Molecular phylogenetics and evolution 2003
Keith L Adams Jeffrey D Palmer

Mitochondrial gene content is highly variable across extant eukaryotes. The number of mitochondrial protein genes varies from 3 to 67, while tRNA gene content varies from 0 to 27. Moreover, these numbers exclude the many diverse lineages of non-respiring eukaryotes that lack a mitochondrial genome yet still contain a mitochondrion, albeit one often highly derived in ultrastructure and metabolic...

Journal: :Current Biology 2015
M. Florencia Camus Jochen B.W. Wolf Edward H. Morrow Damian K. Dowling

Mitochondria underpin energy conversion in eukaryotes. Their small genomes have been the subject of increasing attention, and there is evidence that mitochondrial genetic variation can affect evolutionary trajectories and shape the expression of life-history traits considered to be key human health indicators [1, 2]. However, it is not understood how genetic variation across a diminutive genome...

2016
Anthony P. Khawaja Jessica N. Cooke Bailey Jae Hee Kang R. Rand Allingham Michael A. Hauser Murray Brilliant Donald L. Budenz William G. Christen John Fingert Douglas Gaasterland Terry Gaasterland Peter Kraft Richard K. Lee Paul R. Lichter Yutao Liu Felipe Medeiros Syoko E. Moroi Julia E. Richards Tony Realini Robert Ritch Joel S. Schuman William K. Scott Kuldev Singh Arthur J. Sit Douglas Vollrath Gadi Wollstein Donald J. Zack Kang Zhang Margaret Pericak-Vance Robert N. Weinreb Jonathan L. Haines Louis R. Pasquale Janey L. Wiggs

Purpose Recent studies indicate that mitochondrial proteins may contribute to the pathogenesis of primary open-angle glaucoma (POAG). In this study, we examined the association between POAG and common variations in gene-encoding mitochondrial proteins. Methods We examined genetic data from 3430 POAG cases and 3108 controls derived from the combination of the GLAUGEN and NEIGHBOR studies. We c...

2011
James X. Rong Jean-Louis D. Klein Yang Qiu Mi Xie Jennifer H. Johnson K. Michelle Waters Vivian Zhang Jennifer A. Kashatus Katja S. Remlinger Nan Bing Renae M. Crosby Tymissha K. Jackson Sam M. Witherspoon John T. Moore Terence E. Ryan Sue D. Neill Jay C. Strum

Growing evidence indicates that PPARγ agonists, including rosiglitazone (RSG), induce adipose mitochondrial biogenesis. By systematically analyzing mitochondrial gene expression in two common murine adipocyte models, the current study aimed to further establish the direct role of RSG and capture temporal changes in gene transcription. Microarray profiling revealed that in fully differentiated 3...

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