PURPOSE To investigate the safety and potential efficacy of ranibizumab for prevention of radiation complications in patients treated with proton irradiation for choroidal melanoma. METHODS Forty patients with tumors located within 2 disc diameters of the optic nerve and/or macula were enrolled in this open-label study. Participants received ranibizumab 0.5 mg or 1.0 mg at tumor localization ...

Neurofibromatosis type 1 (NF1) is a multi-system genetic disorder involving the cutaneous, nervous, hematopoietic, ocular, and skeletal systems. Almost all individuals with NF1 (>95%) develop benign dermal tumors called cutaneous neurofibromas (cNFs) which frequently lead to significant physical social morbidity. cNFs exhibit high variability in number, subtype, growth rate, anatomic location. ...

The seven papers in this issue of Cancer Control deal with six different types of neoplasms of the eye and orbit: choroidal melanoma, retinoblastoma, primary ocular lym-phoma, conjunctival melanoma, orbital rhabdomyosarco-ma, and orbital meningioma. These tumors all have an obvious anatomic relationship to the anterior visual pathway , yet each has a different histogenesis, clinical presentatio...

This article presents a methodology for two-dimensional modeling of the human eye to analyze heat transfer in biological tissues, this case, ocular tissues. The technique used was finite differences method time domain. With proposal numerical simulation problem, see that type work aims promote development tools help detect errors biomedical engineering. Several medical procedures, including sur...

Background and objective:Many biochemical features of sulfur mustard (SM) intoxication remained unknown. So far, the direct association between biochemical parameter changes and ocular problems in patients exposed to SM is not evaluated.The current study aimed at evaluating the associations between the ocular findings in patients with SM intoxication and the changes of...

purpose: to present a case of orbital granular cell tumor, a rare orbital tumor. case report: a 55-year-old woman presented with binocular diplopia and right ocular displacement. the problem had initiated 3 years ago. a firm nontender mass at the region of the right lower lid was visible. orbital ct-scan disclosed a well-defined mass in the inferior right orbit with involvement of the inferior ...

a case of pleomorphic adenoma in sweat gland is reported here. the histopathologic report confirmed the diagnosis. pleomorphic adenoma is most common in salivary glands but very rare in sweat glands. pleomorphic adenoma in sweat gland and the similar tumors of eccring sweat gland are described that bear a striking resemblance to pleomorphic adenomas of salivary gland. upon closer examination, t...