the purpose of this study was to investigate the effect of call/web-based instruction on improving efl learners’ pronunciation ability. to this end, 85 students who were enrolled in a language institute in rasht were selected as subjects. these students were given the oxford placement test in order to validate their proficiency levels. they were then divided into two groups of 30 and were rando...

The present work aimed to assess the validity and reliability of the 3D motion analyzer (Shimano Dynamics Lab, Sittard, Netherland) during laboratory cycling tests in comparison with the Vicon device (Vicon Motion Systems Ltd. Oxford, UK). Three cyclists were required to complete one laboratory cycling test at three different pedalling cadence and at a constant power output. Kinematic measureme...

This study was an attempt to investigate whether using Instagram had any significant effects on Iranian intermediate autonomous/dependent EFL learners’ pictorial metaphors or not. In doing so, Oxford Placement Test administered among100 learners studying at Rooyesh language institute in Kelishad, Isfahan, Iran; and based the results, 80 were selected. Then, autonomy test conducted divide them i...

This paper presents an empirical analysis of some implementations of tour improvement heuristics designed for the pickup and delivery traveling salesman problem. Results show that while the classical 2-opt traveling salesman algorithm can be implemented very efficiently, available implementations of the 3-opt are much less efficient. Among tested algorithms, the only one to produce significant ...

The problems with high complexity had been the challenge in combinatorial problems. Due to the none-determined and polynomial characteristics, these problems usually face to unreasonable searching budget. Hence combinatorial optimizations attracted numerous researchers to develop better algorithms. In recent academic researches, most focus on developing to enhance the conventional evolutional a...

OBJECTIVES In patients with type 2 diabetes (T2D) and heart failure (HF), the optimal glycemic target is uncertain, and evidence-based data are lacking. Therefore, we performed a randomized study on the effect of optimized glycemic control on left ventricular function, exercise capacity, muscle strength, and body composition. DESIGN AND METHODS 40 patients with T2D and HF (left ventricular ej...

To generate a more efficient in vivo reporter and therapeutic gene, we optimized the coding sequence of the human sodium/iodide symporter (NIS) gene by replacing NIS DNA codons from wild type to new codons having the highest usage in human gene translation. The Codon Adaptation Index (CAI), representing the number of codons effective for human expression, was much improved (0.79 for hNIS, 0.97 ...