Here we report a novel approach for preparation of a 6-day transdermal drug delivery system (TDDS) as treatment for mild to moderate Alzheimer’s disease. The spray drying method was used to prepare microparticles containing the anti-Alzheimer drug. The content of the drug was determined by High Performance Liquid Chromatography (HPLC) method. The morphology and size range of the microparticles ...

Illicit transnational flows of goods, money, information, and people – the clandestine side of globalization – have become a growing source of tension and conflict in world politics. Nevertheless, the illicit dimensions of the global economy are largely overlooked in the international political economy (IPE) literature.1 This is evident by surveying the major textbooks, readers, and journals in...

OBJECTIVE Nightmares are a robust and modifiable predictor of increased suicidality and poor psychiatric outcomes, yet nightmare screening and treatment remain rare, even in sleep centers. This paper aims to examine what proportion of nightmare sufferers have discussed nightmares with a healthcare provider, as well as possible explanations for low rates of nightmare complaints. METHODS The pr...

the dynamic response of a transversely isotropic, linearly elastic layer bonded to the surface of a half-space of a different transversely isotropic material under arbitrary shape surface loads is considered. with the help of displacements and stresses green’s functions, an analytical formulation is presented for the determination of the displacements and stresses at any point in both surface l...