Antioxidant consumption has been reported to be inversely associated with the incidence of coronary artery disease. To clarify the possible role of vitamin E and volatile oils in the prevention of atherosclerosis, the effects of these compounds on the susceptibility of low-density lipoprotein (LDL) to oxidative modification were investigated. In this study, vitamin E and seven volatile oils “an...

Background & Aim: Different species from mint family (Lamiaceae) are used as spices and fragrance in food or as medicine against viral or microbial diseases in many countries for generation. Lamiaceae family contains 46 genus and 410 species. One of the valuable and medicinal species of this family is Ziziphora clinopodioides Lam. This species contains the essential o...

Background & Aim:Mentha longifolia (L.) Huds is an aromatic perennial herb that belongs to the   family Lamiaceae. The aim of this study was to identify chemical composition of aerial parts   (including leaf, stem and flowers) of M. longifolia collected from   (Kamu mountain) Isfahan province. Experimental: The essential oils were extrac...

Abstract Flavin‐dependent halogenases (FDHs) natively catalyze selective halogenation of electron rich aromatic and enolate groups. Nearly all FDHs reported to date require a separate flavin reductase supply them with FADH 2 , which complicates biocatalysis applications. In this study, we establish that the single component reductase/flavin dependent halogenase AetF catalyzes diverse set substr...

The partial purification of the enzyme, aromatic aldehydeketone reductase (aromatic A-K reductase), from rabbit kidney cortex is described. Aromatic A-K reductase utilizes TPNH but not DPNH as a cosubstrate. Substituted benzaldehydes and acetophenones are readily reduced to carbinols. Aromatic A-K reductase does not, however, catalyze the reverse reaction, the dehydrogenation of carbinols under...

Rat liver microsomal 3-hydroxy-3-methylglutaryl-CoA reductase [HMG-CoA reductase; mevalonate:NADP+ oxidoreductase (CoA-acylating), EC 1.1.1.34], the key regulatory enzyme in cholesterol biosynthesis, has been purified to apparent homogeneity. Purified HMG-CoA reductase yields a single diffuse band when NaDodSO4/polyacrylamide gels are stained with Coomassie blue and yields two adjacent bands wh...