in recent years many researchers have been focused on interaction of small molecules with dna. dna is generally the primary intracellular of anticancer drugs, so the interaction between small molecules and dna can cause dna damage in cancer cells, blocking the division of cancer cells and resulting in cell death. the flavonoids are a large group of polyphenolic natural products that are widely ...

  Background and purpose: Increased production of free radicals occurs due to intense and unconventional physical activity. The present study aimed at evaluating the effect of six weeks of high intensity interval training and Matcha green tea on some cellular oxidants (MDA) and glutathione peroxidase (GPX) in women. Materials and methods: A quasi-experimental applied research was performed in...

Background & Aim: The supplements and exercise training are used to diabetes control. The purpose of this study was to investigate the effect of eight weeks high intensity interval training and caffeine intake on glycemic indices and insulin resistance in diabetic rats. Methods: In a quasi-experimental study, 50 Wistar diabetic male rats were randomly divided into five groups including control...

Introduction and purpose: Most cardiovascular diseases can be prevented by regular exercise and the use of herbal supplements. Therefore, the aim of the present study was to investigate the effect of six weeks of High-intensity interval training (HIIT) and fenugreek supplementation on plasma levels of C-reactive protein and cortisol in overweight and obese women. Materials and Methods: In this ...

Background: One of the most common problems in diabetic patients is muscle atrophy. Therefore, the present study aimed to investigate the synergistic effect of endurance training with probiotic supplementation on Atrogin-1 and MuRF-1 genes gene expression in the soleus muscle of diabetic rats. Methods: In this study, 32 male Wistar rats were randomly divided into one normal control (NC) and fo...

Background: Addiction dependency presents itself as change in the level of protective proteins of airways and increase in stress. The purpose of this study was to determine the effect of aerobic training on Clara Cell protein 16 (CC16) and cortisol in addicts. Methods: In this semi-experimental study, 20 addicted men (20-33 years old) were selected after public call and divided into drug...

abstract part one: the electrode oxidation potentials of a series of eighteen n-hydroxy compounds in aqueous solution were calculated based on a proper thermodynamic cycle. the dft method at the level of b3lyp-6-31g(d,p) was used to calculate the gas-phase free energy differences ,and the polarizable continuum model (pcm) was applied to describe the solvent and its interaction with n-hydroxy ...

in this research we have studied the effect of some transition-metals (cu, ag and au) substitutions on two-electron reduction potential of flavins by application of dft method. all geometries have been optimized at blyp level of theory and “6-31+g** + lanl2dz” mixed basis set. the frequency job at the same method and basis sets has been performed to obtain gibbs free energy of compounds. it h...