A comprehensive and facile method for the synthesis of new functionalized bis-heterocyclic compounds containing a thieno[2,3-b]thiophene motif is described. The hitherto unknown bis-pyrazolothieno[2,3-b]thiophene derivatives 2a-c, bis-pyridazin othieno[2,3-b]thiophene derivatives 4, bis-pyridinothieno[2,3-b]thiophene derivatives 6a,b, and to an analogous bis-pyridinothieno[2,3-b]thiophene nitri...

Psychopathic individuals are generally unresponsive to motivational and emotional cues that facilitate behavioral regulation. A putative mechanism for this deficiency is Gray’s (1981) behavioral inhibition system (BIS). To evaluate the association between psychopathy and BIS functioning, we administered a laboratory-based assessment of BIS functioning to a group of psychopathic offenders assess...

study of correlation of glasgow coma score and bispectral index in mild and moderate traumatic brain injuries     feizi a [1] , jarineshin h* [2] , estabragnia h [3] , mahoori a [4] , khalkhali h [5] , sattari s [6]     received: 3july, 2011 accepted: 23september, 2011     abstract   background & aims : it is important to monitor the state of consciousness in patients suffering from traumatic b...

UNLABELLED The aim of this study was to analyze the electroclinical features and evolution in patients with benign infantile seizures (BIS) associated with paroxysmal dyskinesia (PD). PATIENTS AND METHODS Among 198 patients with BIS (78 of whom were familial cases), we evaluated 12 unrelated patients with BIS and PD seen at two pediatric neurology departments from January 1990 to February 200...

neutral bidentate n-o type complexe of vo(ii) has been synthesized through condensation of dpenicillamine,(d-h2pen), with bis(acetylacetonate)- oxovanadium(iv),[vo(acac)2], at neutralmedium . the established schiff base(no type) complex was characterized on the basis of ir andmass spectroscopy techniques.besides,d-h2pen binding behavior to[vo(acac)2] has been studiedin thermodynamic viewpoint u...

objective: evaluating the effect of dentin conditioning with edta on microleakage of composite resin restorations, using two etch and rinse and two self-etch adhesives. materials and methods: one hundred and sixty extracted molars received class v cavity preparations right under the cej and were randomly divided into eight groups of 20, usingfour different adhesive systems. these adhesives incl...

Organoboranes carrying electron-withdrawing substituents are commonly used as Lewis acidic catalysts or cocatalysts in a variety of organic processes. These Lewis acids also became popular through their application in `frustrated Lewis pairs', i.e. combinations of Lewis acids and bases that are unable to fully neutralize each other due to steric or electronic effects. We have determined the cry...

INTRODUCTION To investigate the effects of bisphosphonates (Bis) (etidronate, alendronate, and risedronate), alone and in combination with statin, on the BMD (bone mineral density) and bone metabolism of rheumatoid arthritis (RA) patients. METHODS Seventy-seven RA patients who had been receiving prednisolone (PSL) and Bis for over 4 years were divided into two groups: Bis and Bis + statin (n ...