BACKGROUND Radiofrequency ablation (RFA) for atrioventricular nodal reentrant tachycardia appears to reduce atrial tachycardia, which might relate to parasympathetic denervation at cardiac ganglionated plexuses. METHODS AND RESULTS Compared to 7 control canines without RFA, in 14 canines, RFA at the bottom of Koch's triangle attenuated vagal stimulation-induced effective refractory periods pr...

To cite: Akhtar W, Rathod KS, Alexander J, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013010474 DESCRIPTION We present a case of profound first-degree heart block with the longest reported PR interval (640 ms). The aetiology of extreme first-degree block in our case was multifactorial, due to senile conductive system fibrosis, hypothermia and digoxin ...

AIMS This study aimed to clarify the safety and efficacy of selective fast pathway ablation in patients with atrioventricular nodal reentrant tachycardia and a prolonged PR interval during sinus rhythm. Such patients have been reported to have an increased incidence of complete atrioventricular block. METHODS AND RESULTS In this study, the earliest retrograde atrial activation during atrioven...

Abstract Introduction: Isolated perfused heart models such as perfusion and superfusion are commonly used for mammalian heart research. However, there are several fundamental limitations in the current techniques. In perfusion model, a suitable cannula is connected to the aorta and the perfusion is retrogradely performed. But, electrode displacement is a potential unwanted event resulted fr...

THE CONCEPT of concealed conduction was introduced into electrocardiography to explain a lengthening of, or change in, the refractory period of the atrioventricular conduction system caused either by atrial activity that fails to propagate to the ventricles or by ventricular activity that fails to reach the atria. Standard electrocardiograms do not provide a direct demonstration of the partial ...

We examined the effects of stellate ganglia stimulation on the phase-dependent chronotropic and dromotropic responses to brief vagal bursts in open-chest anesthetized dogs. Stellate stimulation affected the phasic vagal effects on heart rate by shortening the latent period, shifting the phase at which maximum decrease in heart rate occurred to earlier phases, and reducing the maximum decrease i...

Introduction Cardiac resynchronization therapy (CRT) has shown a significant clinical benefit over right ventricular pacing in patients with left ventricular dysfunction and a high ventricular pacing requirement. Traditionally, CRT has relied on coronary sinus (CS) lead placement through the use of fluoroscopy and venography. Three-dimensional (3D) electroanatomic mapping has been used as an al...