نتایج جستجو برای: cell and tissue
تعداد نتایج: 17165958 فیلتر نتایج به سال:
Background and purpose: Articular cartilage disease is prevalent in all societies and in most cases the damaged cartilage would not repair. Conservative treatments are associated with many problems. So cell therapy is needed as a definite treatment. One of the best and most accessible sources of cells for this purpose is stem cells derived from adipose tissue which can be differentiated into ch...
Backgrounds: Evidence is accumulating to support disruption of tissue architecture as a powerful event in tumor formation. For the past four decades, intensive cancer research with the premise of “cancer as a cell based-disease” focused on finding oncogenes or tumor suppressor genes. However, the role of the tissue architecture was neglected. Three dimensional (3D) cell cultures which can recap...
Abstract Background: The amniotic membrane has gained much attention in regenerative medicine as a precious cell source. Recently, reparation of three dimensional matrices (scaffold) with appropriate specificity for cell culture, which depends on cell type, has been the subject of many studies .This study aimed to design optimal three-dimensional matrices in order to utilize amniotic epithel...
background: because of the ability of proliferation, regeneration, conversion to differentiated cells and tissue producing, stem cell therapy has important clinical implications for treatment of different diseases. in this chapter we discuss different kinds of stem cells that have been used in treatment of neurologic diseases, gastrointestinal diseases, heart diseases, bone disease, kidney dise...
introduction perforation of maxillary sinus mucous membrane is of the most prevalent complication during open sinus lift surgery. moreover, such complication can usually be managed by an absorbable membrane. as far as absorbable membranes are concerned, decellularized maxillary sinus mucous membranes, which is an extracellular matrix, can be used as a biologic scaffold and insulating membrane i...
Recently, it has been proven that cartilage healing is difficult. The most commonly used treatments are autogenously cartilage grafting and allogeneic bone grafting, but grafts cannot fully meet treatment goals because of source, price, safety, and other concerns. Thus, a combination of biological materials and tissue engineering technology has become a recent trend in studies. Among the studie...
Background: Adipose tissue stem cells (ASCs) cause faster repair of damaged tissue posttransplantation by releasing growth factors in neurodegenerative diseases. ASCs secrete factors in the culture medium called conditioned medium (CM) in vitro. This study investigated the expression of neurotrophin genes in vitro culture and transplant of ASCs in Parkinsonian rats. Materials and Methods: In th...
Background and Objective: Various diseases and injuries can lead to loss cartilage tissue. Cartilage tissue engineering based on the use of stem cells which has provided a promising opportunity to repair damaged tissue. Recently, adipose-derived mesenchymal stem cells (ADSCs) have captured considerable scientific and clinic interest because of their easy access, rapid expansion in vitro...
Background: Human Cripto-1, a member of the EGF-CFC family, is involved in embryonic development, embryonic stem cell maintenance, and tumor progression. It also participates in multiple cell signaling pathways including Wnt, Notch, and TGF-β. Remarkably, it is expressed in cancer stem cell (CSC) compartments, boosting tumor cell migration, invasion, and angiogenesis. Although Cripto-1 is ...
background: based on recent studies, there are controversial reports on the ca-pacity of tissue cyst forming of toxoplasma gondii rh strain. in this study, the capac-ity was evaluated by in vivo and in vitro experiments. methods : rh strain was subcutaneously inoculated to ten wistar rats. after one month, their blood, brain, tongue and diaphragm were collected and evaluated by mat, pcr, pathol...
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