The Cbl proteins (Cbl, Cbl-b, and Cbl-c) are a highly conserved family of RING finger ubiquitin ligases (E3s) that function as negative regulators of tyrosine kinases in a wide variety of signal transduction pathways. In this study, we identify a new Cbl-c interacting protein, Enigma (PDLIM7). This interaction is specific to Cbl-c as Enigma fails to bind either of its closely related homologues...

While in Paper I of four papers a revised columnar high-order modelling approach to investigate gas-aerosolturbulence interactions in the convective boundary layer (CBL) was deduced, in the present Paper II the model capability to predict the evolution of meteorological CBL parameters is demonstrated. Based on a model setup to simulate typical CBL conditions, predicted first-, secondand thirdor...

the present study intended to look into and compare the possible effects of competitive team-based learning (ctbl) with learning together (lt) or cooperative group-based learning (cgbl) – the most popular method of cooperative learning (cl) -- on oral performance of iranian efl intermediate students. after administering the oral interview, this researcher selected a group of 40 almost homogeneo...

this study aimed at investigating the impact of utilizing call on efl learners’ foreign accent reduction. to this end, 62 participants out of 100 undergraduate freshman english students at islamic azad university central tehran branch were ed based on a piloted sample pet and a text-to-read. the ed participants were then nonrandomly assigned to an experimental and a control group, each containi...

In this opinion article, the authors share their experiences with and perspectives on course design requirements barriers when applying challenge-based learning (CBL) in an online sustainability education setting. CBL is established approach for (higher) education. It enables teachers to engage students open, real-life grand challenges through inter-/transdisciplinary student team collab...