نتایج جستجو برای: corneal scar
تعداد نتایج: 42142 فیلتر نتایج به سال:
PURPOSE Thrombospondin-1 (THBS1) has been suggested as a corneal wound-healing modulator. Therefore, we compromised the integrity of the cornea to elucidate the role of THBS1. METHODS Full-thickness penetrating corneal incisions (1.5 mm) were created in wild type (WT, 129S2/SvPas) and THBS1-deficient mice (Thbs1⁻/⁻), 129S2/SvPas-Thbs1(tm1Hyn)/Thbs1(tm1Hyn)), and allowed to heal up to 1 month,...
Corneal transparency is attributed to the regular spacing and diameter of collagen fibrils, and proteoglycans may play a role in fibrillogenesis and matrix assembly. Corneal scar tissue is opaque and this opacity is explained by decreased ultrastructural order that may be related to proteoglycan composition. Thus, the objectives of the present study were to characterize the proteoglycans synthe...
To the Editor: Flap creation is the most crucial step of LASIK and the introduction of the femtosecond laser led to the production of uniform flaps enhancing the accuracy and reproducibility of LASIK.1,2 However, intrastromal corneal opacity (such as scar and haze) raised controversies regarding the efficacy of the technique in such cases because it can interfere with laser tissue disruption, c...
INDICATIONS for lamellar corneal grafts are somewhat more numerous than those for penetrating keratoplasty, and Paufique, Sourdille, and Offret (1948) mention, besides the usual optical reason for replacing a corneal scar, tectonic, preparatory, aesthetic, and therapeutic indications. This last, designed to interrupt the course of chronic and recurrent corneal disorders, is of peculiar interest...
In the current study, we conducted a mutation screening of tumor-associated calcium signal transducer 2 (TACSTD2) gene in six consanguineous Iranian families with gelatinous drop-like corneal dystrophy (GDLD), in order to find the causative mutations. Detailed eye examination was performed by ophthalmologist to confirm GDLD in patients. To detect the possible mutations, direct Sanger sequencing...
The purpose of this study was to evaluate the effects of different time combinations of dexamethasoneand acetylcysteine on experimentally induced corneal ulcers in dogs. Experimental corneal wounds werecreated surgically to the anterior one third of the cornea in the center of all eyes of 15 mixed breed dogs. The eyes were divided into five groups according to planned post-operative medications...
purpose: congenital corneal leukoma is rare with an incidence of 6/100000 and is one of the most important causes of amblyopia. here we report an unusual case of bilateral congenital elevated corneal leukoma. methods: we encountered a 13-day-old full term male newborn. ocular examination of both eyes revealed central elevated corneal leukomas with a narrow normal lucid interval to limbus. corne...
Keratoconus is an evolving condition. The speed and severity of the course differs from patient to patient. We report clinical observation a 36-year-old with history severe atopy who presents neglected bilateral keratoconus. examination found sign Munson Rizzuti, corneal protrusion being more marked in left eye. Biomicroscopic revealed opacity central right eye thinning. In eye, there was strom...
Report keratoconus in two patients with a long history of wrestling without any risk factor for corneal ectasia and reviewing the possible pathogenesis. To confirm suspicion of keratoconus, corneal topography was performed using scanning slit topography system and Orbscan. In two wrestlers with the complaint of visual loss in their eyes and IOP raising, corneal topography was performed and de...
Background and purpose: Astigmatism is a common optical dysfunction, effective on various visual outcomes and one of the important criteria of refractive surgery. The aim of present study was to evaluate the correlation between refractive, corneal and residual astigmatism in refractive surgery candidates. Materials and methods: In this cross-sectional descriptive, analytical study, 200 patient...
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