Forest automata (FA) have recently been proposed as a tool for shape analysis of complex heap structures. FA encode sets of tree decompositions of heap graphs in the form of tuples of tree automata. In order to allow for representing complex heap graphs, the notion of FA allowed one to provide user-defined FA (called boxes) that encode repetitive graph patterns of shape graphs to be used as alp...

We have previously shown an unbalanced cytokine production in Fanconi anemia (FA) cells, ie, an underproduction of interleukin 6 (IL-6) during growth. Among a number of cytokines analyzed, the only other anomalies detected concern tumor necrosis factor alpha (TNF alpha). In comparison to normal cells, this cytokine is overproduced by FA lymphoblasts from the four genetic complementation groups....

Fanconi anemia (FA) is an autosomal recessive cancer susceptibility syndrome characterized by cellular sensitivity to genotoxic agents. In recent years, FA proteins have been associated with different molecules involved in signal transduction, which has raised the interest in FA-dependent signaling pathways. Here, we report that the c-Jun N-terminal kinase (JNK) fails to phosphorylate in respon...

Background: In certain regions of the brain, aphasia arises from a lack understanding and regulating language following damage. About 35–40 percent people receiving hospitalization after stroke are identified with aphasia. The recently developed imaging methods for analysis impact brain lesion sites sizes on Diffusion Tensor Imaging (DTI) Fractional Anisotropy (FA). order to reflect micro-struc...

Soil organic matter (SOM) is a key factor controlling the fate of hydrocarbons in soils; however, there are no standardized methods to accurately predict their sequestration. This study proposes an accessible analytical tool capacity soil sequester considering chemical characteristics humic (HA) and fulvic acids (FA) SOM. The natural was modified by thermal treatments, obtaining five different ...

Ferulic acid (FA) is a polyphenolic phytonutrient which possesses strong antiproliferative effect; however, it has limited therapeutic applications due to its physiochemical instability and low bioavailability at the tumor site. In present study, these shortcomings associated with FA were overcome by fabricating FA-encapsulated poly(D,L-lactide-co-glycolide)/polyethylene oxide (PLGA/PEO) blend ...

BACKGROUND/AIM Fanconi anemia (FA) is a rare hereditary disease in a heterogeneous group of syndromes, so-called chromosome breakage disorders. Specific hypersensitivity of its cells to chemical agents, such as diepoxybutane (DEB), was used as a part of screening among patients with clinical suspicion of FA. The aim of this study was to determine chromosomal instability in patients with FA symp...

BACKGROUND Diabetic retinopathy is characterized by defects in the retinal neurovascular unit. The underlying mechanisms of impairment-including reactive intermediates and growth-factor dependent signalling pathways and their possible interplay are incompletely understood. This study aims to assess the relative role of hyperglycemia and hyperinsulinemia alone or in combination on the gene expre...