BACKGROUND Diarrhoea is a common occurrence in association with antibiotic administration. Earlier studies and meta-analyses have suggested that probiotic administration reduces the incidence of antibiotic-associated diarrhoea (AAD). AIM To estimate the reduction in risk of AAD with administration of probiotics in randomised placebo-controlled trials and to identify factors associated with su...

Abstract: This paper studies grouped model averaging methods for finite sample size situation. Sufficient conditions under which the grouped model averaging estimator dominates the ordinary least squares estimator are provided. A class of grouped model averaging estimators, g-class, is introduced, and its dominance condition over the ordinary least squares is established. All theoretical findin...

Analyzing the data of individuals has several advantages over analyzing the data combined across the individuals (the latter we term group analysis): Grouping can distort the form of data, and different individuals might perform the task using different processes and parameters. These factors notwithstanding, we demonstrate conditions in which group analysis outperforms individual analysis. Suc...

In the modern Big Data analysis, testing multiple hypotheses simultaneously has been an important tool in analyzing data arising from scientific studies, such as genetics, astronomy, social sciences and many others. The hypotheses can often be grouped together according to the nature of the scientific investigations. For instance, genes can be grouped according to gene pathways; the nearby pixe...

Grouped data occur frequently in practice, either because of limited resolution of instruments, or because data have been summarized in relatively wide bins. A combination of the composite link model with roughness penalties is proposed to estimate smooth densities from such data in a Bayesian framework. A simulation study is used to evaluate the performances of the strategy in the estimation o...

The aim of this paper is to estimate the density f of a random variable X when one has access to independent observations of the sum of K ≥ 2 independent copies of X . We provide a constructive estimator based on a suitable definition of the logarithm of the empirical characteristic function. We propose a new strategy for the data driven choice of the cut-off parameter. The adaptive estimator i...

to conduct a systematic review and meta-analysis on controlled treatment trials of meta-cognitive therapy (mct) for anxiety disorders, studies were included if they employed controlled methodology and treated people above 18 years with anxiety disorders. case studies (with less than 4 cases) and single case designed studies were excluded. a comprehensive literature search identified 15 trials f...