multipotent mesenchymal stem cells (mscs) are recently found to alter the tumor condition. however their exact role in tumor development is not yet fully unraveled. mscs were established to perform many of their actions through paracrine effect. thus investigation of msc secretome interaction with tumor cells may provide important information for scientists who are attempting to apply stem cell...

Introduction: Streptomyces manage the osmotic stress by collecting compatible solutes or osmolytes. Ectoine, 1,4,5,6-tetrahydro-2-methyl-4-pyrimidine carboxylic acid, and 5-hydroxyectoine are among the most common osmolytes of this bacteria and have an active role in protecting the genetic material of this microorganism as well as providing resistance to environmental pressures. In this researc...

background: radiation-induced lung injury is a refractory side effect in lung cancer radiotherapy, the mechanism still remains unclear, hence an appropriate animal mode may become useful to investigate it. materials and methods: 50 female wistar rats were randomly divided into 5 groups, average 10 rats/cage: a. control group b. 3gy×10f c. 6gy×5f d. 12.5gy×1f e.15.3gy×1f. by different doses of r...

Introduction:   The aim of this study is to investigate the effect of respiratory motion during radiation therapy in patient with lung cancer and comparison of dosimetric parameters between Intensity modulation radiation therapy and three-dimensional conformal radiotherapy in lung cancer.   Materials and Methods:   Two CT scan was performred for each pati...

Immuno-oncology marked a therapeutic revolution in the treatment of cancer. Thanks to new strategy that aims awaken immune system fight cancer cells, there has been change clinical course advanced Non- Small Cell Lung Cancer (NSCLC). Our study aimed evaluate efficacy nivolumab monotherapy patients with stage IIIB/IV non-small cell lung beyond second line. The results showed progression-free sur...

Background: Inclusion of inhomogeneity corrections in intensity modulated small fields always makes conformal irradiation of lung tumor very complicated in accurate dose delivery.Objective: In the present study, the performance of five algorithms via Monte Carlo, Pencil Beam, Convolution, Fast Superposition and Superposition were evaluated in lung cancer Intensity Modulated Radiotherapy plannin...

Lung cancer begins in the lungs and leading to reason of demise amid population creation. According American Cancer Society, which estimates about 27% deaths because cancer. In early phase its evolution, lung does not cause any symptoms usually. Many patients have been diagnosed a developed where become more prominent, that results poor curative treatment high mortality rate. Computer Aided Det...

Spontaneous pneumothorax (SP) is usually attributed to the rupture of subplural bubbles and rarely associated with lung cancer. Pneumothorax may be first sign The most common possibility that SP complicates cancer mechanism tumour necrosis or, in separate cases, emphysematous bubbles. Lung should always considered as a possible cause MS elderly patients or heavy smokers. We report case an 75-ye...