background: this study attempts to ascertain a reliable cutoff size to determine whether pelvic lymph nodes are metastatic or not in ovarian cancer patients. methods: we retrospectively reviewed 73 pet/ct scans of 52 female patients with ovarian carcinoma who underwent surgery followed by chemotherapy. the findings of contrast enhanced mdct were interpreted by two experienced radiologists unawa...

Surgical treatment for mediastinal lymph node involvement in non-small cell lung cancer (NSCLC) will not have positive impact on survival. The present study aimed at investigating the role of positron emission tomography/computerized tomography (PET/CT) in staging NSCLC. Ninety-nine patients with maximal standard mediastinal lymph node involvement value (SUVmax) of 2.5 or more on PET/CT scannin...

The connective tissue of any organ in the body is generally referred to as stroma. This complex network is commonly composed of leukocytes, extracellular matrix components, mesenchymal cells, and a collection of nerves, blood, and lymphoid vessels. Once viewed primarily as a structural entity, stromal cells of mesenchymal origin are now being intensely examined for their ability to directly reg...

Objective(s): Malignant melanoma is the most lethal type of skin cancers with unfavorable prognosis. Alpha-MSH peptide analogues have a high affinity for melanocortine-1 (MC1) receptors on melanocytes overexpressing in malignant melanoma cells. Pre-clinical studies have shown promising results for radiolabeled MSH imaging in this malignancy. The purpose of this study is to assess the diagnostic...

we report a young male with an initial excisional biopsy report of melanoma of the lower back, referred to our hospital for complete excision and sentinel lymph node (sln) biopsy.  four peritumoral intradermal tc-99m phytate injection was performed and slns were detected in both axillary and right inguinal regions. on the biopsy only the right axillary sln was metastatic leading to right axilla...

STUDY OBJECTIVE To reevaluate whether it is possible to reliably differentiate malignant mediastinal lymph nodes from benign nodes by size, and to determine the frequency of metastases to normal-sized mediastinal lymph nodes that directly affects the sensitivity for detecting malignant mediastinal lymph nodes (N2 nodes) on CT. DESIGN Prospective study of patients with non-small cell lung canc...

Previous studies have reported that basic fibroblast growth factor (bFGF) is associated with tumor genesis, growth and prognosis. The present study was conducted to detect the levels of bFGF expression in women with non-small cell lung cancer (NSCLC), colon cancer, breast cancer and melanoma, and analyze its association with the clinicopathological characteristics of malignant tumors. The tumor...

aim : the aim of this study was to comprehensively analyze histopathologic parameters of whipple pancreaticoduodenectomy specimens at taleghani general hospital pathology department. background : the whipple procedure is performed for variety of tumors involving the head of the pancreas, ampulla of vater, common bile duct, or duodenum. patients and methods : records of all cases of whipple panc...

OBJECTIVE Endobronchial ultrasound elastography is a new technique for describing the stiffness of tissue during endobronchial ultrasound-guided transbronchial needle aspiration. The aims of this study were to evaluate the utility of endobronchial ultrasound elastography for mediastinal and hilar lymph nodes, and to compare the elastographic patterns of lymph nodes with results from endobronchi...