Development of an appropriate dissolution method for quality control purposes requires consideration of many factors and a balance of different needs. The method is typically distinctive to each drug product because of the unique characteristics of the active ingredient, the formulation, and the manufacturing process. The method development and selection process remains subjective due to the po...

The growth in demand for semiconductors has been accompanied by intense competition between semiconductor manufacturers to satisfy customer on-time delivery needs. This paper is motivated by scheduling the wafer fabrication phase of 300-mm semiconductor manufacturing, as it contains both batch processing operations and multiple customer orders being grouped into production jobs. The resulting m...

This paper presents and analyzes a comprehensive model for the design of cellular manufacturing systems (CMS). A recurring theme in research is a piecemeal approach when formulating CMS models. In this paper, the proposed model, to the best of the authors’ knowledge, is the most comprehensive one to date with a more integrated approach to CMS design, where production planning and system reconfi...

A computer code is developed to accurately simulate the three-dimensional heat transfer during the thermoset fiber placement composite manufacturing process. The code is based on the Lagrangian formulation of the problem. Eight-node brick elements are employed, and the 2 2 2 integration rule is used to numerically evaluate the integrals over an element. The coupled ordinary differential equatio...

Starting from the seminal intuitions that led to the developments of the Economic Order Quantity model and of the formulation of the Dynamic Lot Sizing Problem, inventory models have been widely employed in the academic literature and in corporate practice to solve a wide range of theoretical and real-world problems, as, through simple modifications to the original models, it is possible to acc...

In this paper we present EPIC, a new generic and unified formulation to seamlessly combine the advantages of various types of lithographic hotspot detection techniques. With such formulation, we develop an efficient CAD flow and optimize it with quadratic programming techniques under industry-strength data at an advanced lithography node. After integrating various machine learning and pattern m...

Computer-aided process planning has been recognized as an important tool for coordinating the different operations involved in making the product. While temporal knowledge is central to the design of efficient and reliable process plans, little attention is given to the integration of process planning and temporal processing and reasoning. To fill the void, we propose in this paper a practical ...

Sheet metal bending press-brakes can be setup to produce more than one type of part without requiring a setup change. To exploit this flexibility, we need setup planning techniques so that press-brake setups can be shared among many different parts. In this paper, we describe algorithms for partitioning a given set of parts into setup compatible part families that can be produced on the same se...

Solid models may be blended through filleting or rounding operations that typically replace the vicinity of concave or convex edges by blends that smoothly connect to the rest of the solid’s boundary. Circular blends, which are popular in manufacturing, are each the subset of a canal surface that bounds the region swept by a ball of constant or varying radius as it rolls on the solid while main...