Many anticancer drugs in clinical use interact with DNA through intercalation, which is process that starts with the transfer of the intercalating molecule from an aqueous environment to the hydrophobic space between two adjacent DNA base pairs. In general, intercalatig agents are two types: monofunctional and bifunctional. Monofunctional intercalators contain one intercalating unit and Bifunct...

Accurate unsupervised learning of phonemes of a language directly from speech is demonstrated via an algorithm for joint unsupervised learning of the topology and parameters of a hidden Markov model (HMM); states and short state-sequences through this HMM correspond to the learnt sub-word units. The algorithm, originally proposed for unsupervised learning of allophonic variations within a given...

sleep stages classification is one of the most important methods for diagnosis in psychiatry and neurology. in this paper, a combination of three kinds of classifiers are proposed which classify the eeg signal into five sleep stages including awake, n-rem (non-rapid eye movement) stage 1, n-rem stage 2, n-rem stage 3 and 4 (also called slow wave sleep), and rem. twenty-five all night recordings...

A new automatic speech segmentation procedure, called the \Blind" speech segmentation, is presented. This procedure allows a speech sample to be segmented into sub-word units without the knowledge of any linguistic information (such as, orthographic or phonetic transcription). Hence, this procedure involves nding the optimal number of sub-word segments in the given speech sample, before locatin...

101 isolates of brucella spp. including the reference (n=7) and the iranian field strains belonging to last years 1961-2003 (n=94) were biotyped and classified into 9 biotypes. random amplified polymorphic dna (rapd) analysis using a ten mer-ap4 primer was generated 72 reproduciable dna band. the typeability was 100%. the thirteen isolates were classified into five groups, each containing 2-4 b...

Infants' perception of object boundaries was studied using reaching and preferential looking methods. In 3 reaching studies, S-month-old infants viewed 2 adjacent or separated objects that were stationary, moved together, or moved separately. Infants reached for the objects as distinct units when they moved separately or were separated in space and otherwise reached for the objects as 1 unit. I...

abstract background and purpose: according to the reported problems in area of the inappropriateness of water quality which used for washing and staining of car apparatuses in a car factory, this research was carried out for identification of physical, chemical, and microbiological characteristics of the consumed water in babol car factory, iran. materials and methods: physical and chemical par...