Necroptosis is a highly inflammatory form of programmed cell death that results from MLKL-mediated disruption of the cell membrane. In this issue of Cell, Gong et al. challenge the notion that MLKL activation is a point of no return by identifying mechanisms to counterbalance necroptosis, sustain plasma membrane integrity, and prolong cell viability.

Cold stress is an ‎important limiting factor for cereal production. Barley is a host species for arbuscular mycorrhizal fungi (AMF) with a high genetic diversity in response to cold stress. In order to explore the mechanisms for the ameliorative effect of AMF under cold stress, an experiment was undertaken using completely randomized block design with three factors including temperature treatme...

There is growing concern over the effect of sperm cryopreservation on DNA integrity and the subsequent development of offspring generated from this cryopreserved material. In the present study, membrane integrity and DNA stability of Xenopus laevis and Xenopus tropicalis spermatozoa were evaluated in response to cryopreservation with or without activation, a process that happens upon exposure t...

Background: Exposure of sperm membranes to Reactive Oxygen Species induces lipid peroxidation causing membrane breakdown and loss of function. A rosemary extract as dietary additive was assayed for antioxidant effectiveness to improve the quality of rooster semen. Although rosemary extract has been evaluated for in vitro study of semen preservation, up to date no study has been conducted to exa...

Cell morphogenesis is a complex process that depends on cytoskeleton and membrane organization, intracellular signalling and vesicular trafficking. The rod shape of the fission yeast Schizosaccharomyces pombe and the availability of powerful genetic tools make this species an excellent model to study cell morphology. Here we have investigated the function of the conserved Kin1 kinase. Kin1-GFP ...

The unexpected enhancement of alkalinee phosphatase (ALP) activity in the serum of a group of STZ-diabetic rats recieving the Teucrium polium extract (with hypoglycaemic property) may be attributed to its probable side effects. In order to get a more precise knowledge about this subject, we evaluated the effect of T. polium extract on the plasma membrane ALP activity of K562 cell line. Our data...