نتایج جستجو برای: platelet immunofluorescence test
تعداد نتایج: 942093 فیلتر نتایج به سال:
BACKGROUND Each year, millions of platelet transfusions save the lives of cancer patients and patients with bleeding complications. However, between 10 and 30% of all platelet transfusions are clinically ineffective as measured by corrected count increments, but no test is currently used to identify and avoid these transfusions. ThromboLUX(®) is the first platelet test intended to routinely cha...
A test for platelet antibodies based on the inhibition of migration of platelets from a capillary tube is described. The technique is simple and is capable of detecting antibodies directed against HL-A antigens and the platelet-specific antigen, Pl-A1. Inhibitory activity was detected in sera from two of seven patients with idiopathic thrombocytopenic purpura. The platelet migration inhibition ...
OBJECTIVES This prospective randomized study investigated platelet-induced upregulation of Mac-1 on monocytes and its inhibition by glycoprotein (GP) IIb/IIIa blockage in patients with acute myocardial infarction (AMI). BACKGROUND In experimental AMI, Mac-1 on leukocytes is the pivotal adhesion molecule for detrimental inflammatory responses. In vitro, platelet adhesion to monocytes upregulat...
New indirect immunofluorescence assay as a confirmatory test for human immunodeficiency virus type 1
Background and purpose: Cold storage results in clustering of gpIbα molecules on platelets. Consequently, the lectin domains of αMβ2 receptors on the liver macrophages recognize these molecules and ingest the platelets. Probably coverage of sugar molecules of gpIbα using galactose could prevent the recognition and ingestion of platelets by macrophages. The purpose of this study therby was to...
The origin of platelet alpha-granule fibrinogen (Fg), whether from endogeneous synthesis or exogeneous derivation, remains unknown. Although Fg biosynthesis by megakaryocytes (MK) has been suggested, recent studies have demonstrated that certain alpha-granular proteins originate primarily from plasma. To study the origin of alpha-granule Fg, platelet-associated Fg was measured by ELISA and West...
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