This study evaluates the effects of KM infrastructure and KM processes on the organization’s KM effectiveness. The moderating effect of interpersonal trust on the relationship between KM processes and KM effectiveness is also explored. KM infrastructure has three sub-constructs: KM technology, KM structure, and KM culture; whereas the four sub-constructs forming KM processes are: knowledge acqu...

Daniels, Porteny and Urrutia et al make a good case for the idea that that public decisions ought to be made not only “in the light of” evidence but also “on the basis of” budget impact, financial protection and equity. Health technology assessment (HTA) should, they say, be accordingly expanded to consider matters additional to safety and cost-effectiveness. They also complain that most HTA re...

The purpose of this paper is to explore the field of Risk Management (RM) in relation with Knowledge Management (KM). It attempts to present a conceptual framework, called Knowledge-Based Risk Management (KBRM) that employs KM processes to improve its effectiveness and increase the probability of success in innovative Information Technology (IT) projects. It addresses initiatives towards employ...

We consider the problem of assessing new and existing technologies for their cost-effectiveness in the case where data on both costs and effects are available from a clinical trial, and we address it by means of the cost-effectiveness acceptability curve. The main difficulty in these analyses is that cost data usually exhibit highly skew and heavy-tailed distributions, so that it can be extreme...

Recently, there has been much interest in using the cost-effectiveness acceptability curve (CEAC) to measure the statistical evidence of cost-effectiveness. The CEAC has two well established but fundamentally different interpretations: one frequentist and one Bayesian. As an alternative, we suggest characterizing the statistical evidence about cost-effectiveness using the likelihood function (t...

BACKGROUND The National Department of Health of South Africa decided to start a programme to train mid-level healthcare workers, called clinical associates, as one of the measures to increase healthcare workers at district level in rural areas. Unfortunately, very little is known about the cost effectiveness of clinical associates. AIMS To determine, on a provincial level, the cost effectiven...

We appreciate the efforts of the California Air Resources Board (CARB) to develop economic frameworks and tools for the package of policies necessary to implement California Global Warming Solutions Act of 2006 (AB 32) and meet the requirements of the law. These comments are submitted in anticipation of the June 3, 2008 Economic Analysis Technical Stakeholder Working Group meeting, which will f...