The purpose of this work was to introduce a new concept of coated pellets containing chitosan microspheres loaded with didadosine for oral administration, aiming at reducing the frequency of administration and improving the bioavailability by a suitable release profile. Chitosan microspheres were produced under fluidized bed, followed by extrusion and spheronization to obtain pellets with a mea...

Biocompatible quercetin nanovesicles were developed by coating polyethylene glycol-containing vesicles with chitosan and nutriose, aimed at targeting the colon. Uncoated and coated vesicles were prepared using hydrogenated soy phosphatidylcholine and quercetin, a potent natural anti-inflammatory and antioxidant drug. Physicochemical characterization was carried out by light scattering, cryogeni...

Multifunctional mulberry silk fabrics with excellent temperatureand pH-sensitivity, antibacterial properties and permeability are successfully prepared by surface modification with PNIPAAm/chitosan/poly(ethylene oxide) nanofibers. The nanofibers deposited on the surface of mulberry silk fabric are produced by the electrospinning technique. The surface properties of mulberry silk fabrics were ch...

Active coating systems are a promising postharvest strategy for managing quality attributes while controlling diseases of fresh fruit. This work aims to determine the respiration, quality, antioxidant attributes, and shelf life mango treated with different natural antifungal coatings produced by Lacto-fermented compounds. The respiration rates were modeled using uncompetitive Michaelis-Menten m...

Pellets containing theophylline as a model drug and microcrystalline cellulose, in a ratio of 6:4, were prepared by the extrusion-spheronization method. The pellets were coated with Eudragit RS aqueous dispersions, containing various amounts of pectin-chitosan complex and different coating mass gains, using a fluidized-bed apparatus. Twelve formulations were developed, which differed in two fac...