milk thistle (silybum marianum l. gaertner) is an annual or biannual plant of the asteraceae family. this species is important not only as a medicinal plant traditionally, but also as an endemic plant to protect vegetative and natural resources in iran. this experiment was carried out to find the most effective treatments to break milk thistle seed dormancy and improve its cultivation in vast s...

High value specialty chemicals are usually obtained from natural products by extracting with generally regarded as safe (GRAS) soh•ents. Because organic solvents are quite often used, high operating and disposal costs often occur. When compared to traditional solvents, water can be viewed as an interesting a/tentative because of its low operating and disposal costs. Milk thistle contains compou...

BACKGROUND The prevalence of chronic renal disease exceeds 10% in industrialized societies. Oxidative damage is thought to be one of the main mechanisms involved in nearly all chronic renal pathologies. OBJECTIVE We aimed to use the oxygen radical absorbance capacity (ORAC) method and a sequential multisolvent extraction process to compare the in vitro antioxidant capacity of 55 medicinal her...

Background: Several clinical studies have been undertaken to investigate the potential therapeutic effects of Silybum marianum (S. marianum) seed extract (silymarin) in Type 2 diabetes mellitus (T2DM) and non-alcoholic fatty liver disease (NAFLD). Objective: We performed the present narrative review to evaluate the efficacy of silymarin supplement for treatment of T2DM and NAFLD. Methods: Elect...