This paper accompanies a lecture given at the 2003 CCP4 Study Weekend on experimental phasing. With the audience of the CCP4 Study Weekend in mind, an overview is given of symmetries of substructures and the implications for single isomorphous replacement and single anomalous diffraction phasing procedures, as well as difference Fourier analyses. Pointers are also provided to practical tools fo...

Waiting in long queue is undesirable due to which in some practical situations customers become impatient and leave the system. In such cases providing additional servers can reduce long queue. This investigation deals with multi-server queueing system with additional servers and discouragement. The customers arrive in poisson fashion and are served exponentially by a pool of permanent and addi...

One of the modern paradigms to develop a system is object oriented analysis and design. In this paradigm, there are several objects and each object plays some specific roles. There is a sequence of activities to develop an analysis model. In the first step, we work in developing an initial use case model. Then in the second step, they identify a number of concepts and build a glossary of partic...

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The schema produces derogatory implications in its practical domain in that working with the elderly is considered as something inferior as “Working with older people is seen as focusing on custodial activities that lack the “excitement” and status of other fields of social work practice” [3]. The schema and its associative labels have also given rise to a loss of voice for the elderly in that ...

An algorithm is presented for the fast and accurate definition of protein structural domains from coordinate data without prior knowledge of the number or type of domains. The algorithm explicitly locates domains that comprise one or two continuous segments of protein chain. Domains that include more than two segments are also located. The algorithm was applied to a nonredundant database of 230...

I argue that taking the Practical Conditionals Thesis (PCT) seriously demands a new understanding of the semantics of such conditionals. Practical Conditionals Thesis: A practical conditional [if A][ought(B)] expresses B’s conditional preferability given A Paul Weirich has argued that the conditional utility of a state of affairs B on A is to be identified as the degree to which it is desired u...