نتایج جستجو برای: talalay method

تعداد نتایج: 1630168  

پایان نامه :دانشگاه آزاد اسلامی واحد علوم پزشکی تهران - دانشکده پزشکی 1389

مقدمه: اندازه گیری فشار خون نوزادان برای بررسی سیستم قلبی – عروقی ایشان لازم است در حالیکه این اندازه گیری به ندرت انجام می شود که شاید ناشی از احتمال کم ابتلای نوزاد به اختلالات فشار خون و عدم وجود مرزبندی های مشخص در خصوص این اختلالات در نوزادان می باشد. از آنجا که در کشور ما روشهای معمول اندازه گیری فشار خون نوزادان بصورت non – invasive در مراکز مرجع اطفال و نوزادان شامل روشهای سنتی مثل flus...

2014
Susan P Foy Ryan B Rountree Joseph Cote Tracy dela Cruz Evan Gordon Erica Trent Alex Franzusoff James B Breitmeyer Stefanie J Mandl

Combining poxvirus-based immunotherapies which “step on the gas” to activate tumor antigen-specific T cell immune responses with immune checkpoint inhibitors (ICIs) which “release the brakes” on the immune system is a promising direction for enhancing cancer immunotherapy. Evidence for the potential clinical benefit from combination immunotherapy was obtained in a Phase I dose escalation trial....

Journal: :Cancer research 1985
T T Chang S C Gulati T C Chou R Vega L Gandola S M Ibrahim J Yopp M Colvin B D Clarkson

Autologous stem cell transplantation using cryopreserved bone marrow offers the opportunity to rescue patients from hematopoietic toxicity caused by intensive chemotherapy. This approach is potentially useful for high-risk leukemias as well as for other cancers. The development of suitable methods for purging malignant cells from the bone marrow will offer a better chance of success for autolog...

2017
Imane Chaib Niki Karachaliou Sara Pilotto Jordi Codony Servat Xueting Cai Xuefei Li Ana Drozdowskyj Carles Codony Servat Jie Yang Chunping Hu Andres Felipe Cardona Guillermo Lopez Vivanco Alain Vergnenegre Jose Miguel Sanchez Mariano Provencio Noemi Reguart Caicun Zhou Peng Cao Patrick C. Ma Trever G. Bivona Rafael Rosell Imane Chaib Niki Karachaliou Sara Pilotto Jordi Codony Servat Xueting Cai Xuefei Li Ana Drozdowskyj Carles Codony Servat Jie Yang Chunping Hu Andres Felipe Cardona Guillermo Lopez Vivanco Alain Vergnenegre Jose Miguel Sanchez Mariano Provencio Filippo de Marinis Antonio Passaro Enric Carcereny Noemi Reguart Charo Garcia Campelo Cristina Teixido Isabella Sperduti Sonia Rodriguez Chiara Lazzari Alberto Verlicchi Itziar de Aguirre Cristina Queralt Jia Wei Roger Estrada Raimon Puig de la Bellacasa Jose Luis Ramirez Kirstine Jacobsen Henrik J. Ditzel Mariacarmela Santarpia Santiago Viteri Miguel Angel Molina Caicun Zhou Peng Cao Patrick C. Ma Trever G. Bivona Rafael Rosell

Background The efficacy of epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (TKIs) in EGFR-mutant non-small cell lung cancer (NSCLC) is limited by adaptive activation of cell survival signals. We hypothesized that both signal transducer and activator of transcription 3 (STAT3) and Src-YES-associated protein 1 (YAP1) signaling are dually activated during EGFR TKI treatment to l...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2008
Shu-Fu Lin Sizhi Paul Gao Daniel L Price Sen Li Ting-Chao Chou Paramjeet Singh Yu-Yao Huang Yuman Fong Richard J Wong

PURPOSE Novel therapeutic regimens are needed to improve the dismal outcomes of patients with anaplastic thyroid cancer (ATC). Oncolytic herpes simplex virus have shown promising activity against human ATC. We studied the application of oncolytic herpes simplex virus (G207 and NV1023) in combination with currently used chemotherapeutic drugs (paclitaxel and doxorubicin) for the treatment of ATC...

Journal: :Molecular cancer therapeutics 2005
Alexandre Bozec Patricia Formento Joseph Ciccolini Raphaëlle Fanciullino Laetitia Padovani Xavier Murraciole Jean-Louis Fischel Gerard Milano

Recent studies suggest the possibility of a direct antiangiogenic effect of anti-epidermal growth factor receptor (EGFR) drugs due to the presence of EGFR on endothelial cells. The aim of this study was to analyze the direct effect on endothelial cells of associating EGFR targeting, vascular endothelial growth factor receptor (VEGFR)-2 targeting, and irradiation. We examined both the cytotoxic ...

2011
Daniele G. Soares Miriana S. Machado C eline J. Rocca Virginie Poindessous Djamila Ouaret Alain Sarasin Carlos M. Galmarini A. P. Henriques Alexandre E. Escargueil Annette K. Larsen

PM01183 is a novel marine-derived covalent DNA binder in clinical development. PM01183 is structurally similar to trabectedin (yondelis, ecteinascidin-743) except for the C subunit, and this modification is accompanied by different pharmacokinetics in cancer patients. We here characterize the interaction of PM01183 with the nucleotide excision repair (NER) pathway in comparison with trabectedin...

Journal: :Cancer research 1991
N Usui E G Mimnaugh B K Sinha

To investigate the possibility that anticancer drugs combined with cytokines may show increased activity, human tumor cells were treated with combinations of human recombinant interleukin 1 alpha (rIL-1 alpha) and etoposide (VP-16). The cytotoxicity of these combinations was evaluated by the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl-tetrazolium bromide assay using rIL-1 alpha-sensitive A375-C6 ...

Journal: :Cancer research 1988
Y Kano T Ohnuma T Okano J F Holland

The effects of vincristine (VCR) in combination with methotrexate (MTX) and other antitumor agents were evaluated by cell growth inhibition assay using a human acute lymphoblastic leukemia cell line (MOLT-3). The data were analyzed with the aid of an isobologram using the concept of an envelope of additivity (G. G. Steel and M. J. Peckman, Int. J. Radiat. Oncol., 5:85-91, 1979). Simultaneous ex...

پایان نامه :دانشگاه بین المللی امام خمینی (ره) - قزوین - دانشکده علوم پایه 1390

بررسی وجود و چندگانگی جوابهای معادلات دیفرانسیل به ویژه با شرایط مرزی اغلب بسی دشوار بوده و همراه با گام های ملالت آور می باشد بطوریکه همواره نیاز به پیش شرط هایی می باشد که معادلات دیفرانسیل با شرایط مرزی مورد نظر باید داشته باشد. بنابراین اثبات آنالیزی وجود و چندگانگی جوابهای مسائل مقدار مرزی غیر خطی اغلب غیر ممکن می باشد. روشهای تقریبی- تحلیلی یا روشهای عددی صرفاً برای بدست آوردن جواب موجود ...

نمودار تعداد نتایج جستجو در هر سال

با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید