Rheumatoid arthritis is not a rare condition in east Iran. We have compiled a study of 76 patients with classic and definite RA in the Rheumatology Department of Ghaem Medical School in east Iran. All patients were admitted for clinical and serological evaluation. In terms of sex ratio, pattern of joint involvement, severity and nodularity, RA in east Iran did not resemble that which has b...

A patient with rheumatoid arthritis (RA), vasculitis, and aortic valve incompetence of the histologically nonspecific type is described. Valve replacement was undertaken, and an excellent haemodynamic result was achieved. Both arthritis and vasculitis subsequently remitted. Valve replacement can be successfully performed in RA despite active vasculitis.

Rheumatoid arthritis patients are susceptible to interstitial lung disease, and joint manifestations of rheumatoid arthritis usually precede lung involvements by several years. Organizing pneumonia, as the first manifestation of rheumatoid arthritis, is extremely rare, and its clinical features remain currently unknown. We present a case and a literature review of patients who were pathological...

Objective: Previous studies have examined the role of sensory nerves and neural mediators in symmetrical joint inflammation and autoimmunity in rheumatoid arthritis (RA). In this study, we sought to examine the association between capsaicin skin test and disease activity in RA patients. Materials and Methods: Eighty RA patients (case group) and 20 healthy volunteers were enrolled in this experi...

Rheumatoid arthritis is a chronic, systemic inflammatory autoimmune disease that, untreated, can lead to permanent joint damage, decrease in quality of life, and disability. Health care professionals play a vital role in caring for patients with rheumatoid arthritis. The therapeutic possibilities in the management of rheumatoid arthritis have changed, with newer biologic therapies that target t...

Polymyalgia rheumatica and rheumatoid arthritis may be difficult to differentiate in elderly patients. Polymyalgic symptoms are common in the prodromal phase of rheumatoid arthritis and, as specific diagnostic tests do not exist for either condition, criteria for diagnosis of the diseases are based largely on clinical features. I2 The presence ofsynovitis similar to rheumatoid arthritis in some...

conclusions our findings suggest that there is an association between the mthfr c677t polymorphism and susceptibility for the development of ra. results our results showed significant differences between the groups with respect to mthfr c677t genotype (p = 0.015) and allele frequencies (0.004). statistical analysis showed that there is no relation between gender, age, and ra risk. however, we fo...

background and objectives rheumatoid arthritis (ra) is a chronic inflammatory disease which is characterized by joint swelling, and synovial inflammation. c reactive protein (crp) and ceruloplasmin (cp) are identified as important biomarkers of ra and various inflammatory diseases. curcumin, a widely used yellow color spice is the most active component of curcuma longa l (turmeric). curcumin co...

BACKGROUND To investigate the associations between HLA-DRB1 shared epitope (SE) alleles and rheumatoid arthritis in subsets of rheumatoid arthritis defined by autoantibodies in three Asian populations from Malaysia. METHODS 1,079 rheumatoid arthritis patients and 1,470 healthy controls were included in the study. Levels of antibodies to citrullinated proteins (ACPA) and rheumatoid factors wer...

The immunohistology of synovium from a tender, swollen knee and peripheral blood cellular immune function were correlated in 24 clinically similar patients with active, seropositive rheumatoid arthritis who were not taking cytotoxic or long-acting antirheumatic drugs. The patients were classified as anergic (n = 6) or nonanergic (n = 18) on the basis of peripheral blood mononuclear cell prolife...