angiotensin converting enzyme (ace; omim: 106180) has an important role in the conversion of angiotensin i to angiotensin ii and degradation of bradykinin. genetic polymorphism i/d (rs4646994) in the gene encoding ace has been well defined. to get more insight into the genetic structure of iranian populations, the distribution of the ace i/d polymorphism among iranians was compared with each ot...

background: sunlight is the main source of vitamin d; therefore, environmental factors might have an important role in the high prevalence of hypovitaminosis d in children. this study aimed to assess the vitamin d status according to the climate of the living area in a nationally representative sample of iranian adolescents. material and methods: this nationwide cross-sectional survey was perfo...

Objective: Vitamin D may affect the modulation of signaling pathways in the central nervous system. We aimed to evaluate the effect of high-dose vitamin D supplementation on neuropsychological functions in female adolescents. Methods: We studied the effects of 9 weeks of vitamin D supplementation (50000 IU vitamin D3 [cholecalciferol]/week) on cognitive abilities and sleep disorders in 940 ado...

Vitamin D resistant rickets with alopecia is a rather rare heritable disease probably caused by a different variety of metabolic disorder of this vitamin. Disturbances of protoplasmic and unclear receptors for vitamin D metabolites in bones and intestinal cells have been proposed as basic mechanism; Alopecia is attributed to hypersensitivity to vitamin D; very much like what usually appears in ...

non:union: is common complication of fracture management. various factors are involved in its occurring. metabolic and endocrine factors are often overlooked. so that aim of study was to evaluate the level of vitamin d and pth in patients with unexplained non:union: and fractures due to low energy trauma. in the case control study, 30 patients with tibial non:union: compared with 32 patients wi...

Background: Sunlight is the main source of vitamin D; therefore, environmental factors might have an important role in the high prevalence of hypovitaminosis D in children. This study aimed to assess the vitamin D status according to the climate of the living area in a nationally representative sample of Iranian adolescents. Material and Methods: This nationwide cross-sectional survey was perfo...

pyrano [2,3-d] pyrimidinone derivatives have received considerable interest from the pharmaceutical industry due to their wide range of interesting biological and therapeutic properties. nano al2o3 was found to be a highly efficient solid acid catalyst for the preparation of pyrano [2,3-d] pyrimidinone derivatives from the reaction of barbituric acid, aryl aldehyde and malononitrile. al2o3 nano...