BACKGROUND AND AIM: The aim of this study was to determine the incidence and relative frequency of oral and pharyngeal cancers in Kermanshah, Iran, from March 1993 until March 2006.METHODS: The data used in this epidemiologic study were extracted directly from pathology records registered in 12 (all) public and private pathology centers of Kermanshah province during the 13-year study period. Th...

Background: Gastrointestinal Cancers are one of the most important causes of mortality of patients in the world as well as in our country. The North of Iran is in Asian belt of esophagus cancer in addition, in other areas of our country gastric cancer is the most common GI Cancer. Because GI Cancers are common in Lorestan, we decided to study them in patients undergo endoscopy and colonoscopy i...

The Epstein-Barr Virus (EBV) is a gamma-herpesvirus involved with variety of human cancers, notably the endemic Burkitt lymphoma and nasopharyngeal carcinoma. In 2004, EBV was described as one first known oncoviruses to encode viral microRNAs (miRNAs), these molecules were found interact host targets. miRNAs modulate biological processes that are critical for carcinogenesis, contributing cell t...

abstract background: gastric cancer is one of the most common cancers in our country. recent studies have shown that adenocarcinoma of the cardia and distal stomach has increased in the past 25 years. however demographic data is lacking in this regard. methods: this study is a retrospective case series study. all records from 460 consecutive patients who were documented pathologically to have g...

Cancer is a complex group of diseases with multiple eventual causes. The underlying causes are not fully known. Thus, learning more about the known causes of cancer is an important issue. Moreover, among these factors, infection and its association to cancers is controversial. Although, it seems that the genome instability of the cells can initiate cancer development. The purpose of this review...

worldwide, thyroid cancers are the most common type of endocrine-related cancers. papillary carcinoma accounts for the most frequent type of thyroid malignancy. a rare variant of papillary carcinoma of the thyroid is the cribriform-morular variant. we report a case of solitary, cribriform-morularvariant of papillary carcinoma in a 55-year-old lady. it is important to identify this variant becau...

abstract bachground and aim: mutation analysis of mitochondrial genome and brca genes are helpful in the early diagnosis of familial breast cancers. in this study, we investigated mitochondrial common deletion and brca mutations through multiplex pcr and clinical parameters for the detection of familial breast cancers in archival breast cancer samples. methods: the multiplex pcr was conducted o...