Serial dilution and single dilution enzyme linked immunosorbent assays (ELISA) were standardised and their sensitivity and specificity were compared for serodiagnosis of Babesia equi infection. The antibody titres of 24 donkey sera of known identity were determined separately by serial dilution ELISA using three different B. equi antigens namely whole merozoite (WM), cell membrane (CM) and high...

The unsteady increase in using pharmaceutical opioids is a phenomenon that has existed in human societies for a long time. Furthermore, the ever-growing trend of addiction to opioids affects communities in various economic, social, and cultural aspects. Since abusing pharmaceutical opioids is a complex dynamic problem, it is extremely difficult to recognize the factors influencing this abuse. T...

The unsteady increase in using pharmaceutical opioids is a phenomenon that has existed in human societies for a long time. Furthermore, the ever-growing trend of addiction to opioids affects communities in various economic, social, and cultural aspects. Since abusing pharmaceutical opioids is a complex dynamic problem, it is extremely difficult to recognize the factors influencing this abuse. T...

This paper presents concepts for dealing with topological information in building information models. On the one hand, it shows how to derive topological relationships from ``traditional'' building models consisting of unconnected B-Rep bodies by means of geometric processing algorithms. On the other hand, it discusses the capabilities of topological building modeling based on relational comple...

BACKGROUND Adverse effects of, and bacterial resistance to, macrolides used to treat Rhodococcus equi infections have prompted search for clinically effective alternative antimicrobials. Liposomal gentamicin (LG) is effective against R. equi in vitro and decreases tissue concentrations of R. equi in experimentally infected mice. Effectiveness of LG treatment of foals with R. equi pneumonia, how...

One of the most difficult tasks in modern day database management systems is information retrieval. Basically, this task involves a user query, written in a high-level language such as the Structured Query Language, and some internal operations, which are transparent to the user. The internal operations are carried out through very complex modules that decompose, optimize and execute the differ...

In this study, the kinetics of specific immunoglobulin G (IgG) isotypes were characterized in Babesia equi (Theileria equi)-infected horses. IgGa and IgGb developed during acute infection, whereas IgG(T) was detected only after resolution of acute parasitemia. The same IgG isotype profile induced during acute infection was obtained by equi merozoite antigen 1/saponin immunization.

Rhodococcus equi is a major cause of pneumonia in domestic animals, especially foals, and an opportunistic pathogen of immunocompromised humans (1). Control of R. equi infections in horses has relied on early detection of subclinical pulmonary disease and treatment with antimicrobial drugs before development of clinical signs (2). However, the onset of clinical signs of R. equi pneumonia in foa...

Improved understanding of the epidemiology of Streptococcus equi transmission requires sensitive and portable subtyping methods that can rationally discriminate between strains. S. equi is highly homogeneous and cannot be distinguished by multilocus enzyme electrophoretic or multilocus sequence-typing methods that utilize housekeeping genes. However, on sequence analysis of the N-terminal regio...