We have proposed and validated the hamster cheek pouch model of oral cancer for boron neutron capture therapy (BNCT) studies and shown that boronophenylalanine delivers potentially therapeutic 36.9 +/- 17.5 ppm boron to tumor tissue with tumor:normal tissue and tumor:blood ratios of 2.4:1 and 3.2:1, respectively. Here we report the first evidence of the usefulness of BNCT for the treatment of o...

F. Garcia∗, O Rodriguez ∗, F. Guzman∗, H.Dias, J.D.T Arruda-Neto , and M.S. Hussein† Instituto de Fisica da Universidade de Sao Paulo C.P.63318, 05315-970 São Paulo, SP, Brazil A. K. Kerman Center for Theoretical Physics, Laboratory for Nuclear Science and Department of PhysicsMassachusetts Institute of Technology-Cambridge, Massachusetts 02139,USA July 29, 1999 Microscopic Combinatorial approa...

The research in NANE group is focused on the development of the NAA (Neutron Activation Analysis) methodologies and on their application to environment, nutrition and epidemiology studies. NANE is a multidisciplinary group that has the collaboration of researchers from different fields of science: environment, chemistry, physics, environmental health, biology, biochemistry and geology. The capa...

Accelerator-based BNCT (Boron Neutron Capture Therapy) facilities are being studied, developed and constructed at many laboratories and hospitals, especially in Japan. In order to provide sufficient neutron flux in the epi-thermal energy region (0.5 ~ 10 keV), an intense proton beam accelerated with a cyclotron, linear accelerator (linac) or DC accelerator up to 2.5 ~ 30 MeV is directed to lith...

Epithermal neutron resonance self-shielding factors in foils of materials used as activation detectors or as targets for radionuclide production have been calculated using the MCNP code. Two irradiation conditions have been considered: (a) foils immersed into an isotropic neutron flux and (b) foils submitted to a collimated neutron beam. The self-shielding factors, Gres(t), for gold, indium, ma...

Despite the existence of a well-known set forecast and search criteria, only three gold silver epithermal deposits were discovered on territory Amguem-Kanchalan metallogenic zone, which has significant resource potential. The base enterprises developing them is extremely limited. aim study to clarify regional local conditions for localization gold-silver mineralization, forecasting searching pr...

Ghana’s highly enriched uranium (90.2%) research reactor has been converted to a low (13.0%) type. Its neutron parameters have characterized for the application of k0-instrumental activation analysis. The magnitude LEU epithermal shaping factor (?) at irradiation site increased by about 25% as compared HEU, while thermal neutrons decreased 5%. This indicates that spectrum is much dependent on 1...

The determination of astrophysically relevant neutron-induced cross sections is particularly difficult when the involved isotopes are radioactive or very small. Activation experiments at reactors offer possibility to overcome these limitations with high neutron fluxes. flux typically based on activation two monitors known separate different components. usually applied cadmium difference method ...

Introduction: Many photogeologic studies and very recent results from orbital geochemical mapping experiments are consistent with the presence of shallow subsurface ice deposits on Mars. The next step in studying these deposits will be to visit them on the surface, probably with mobile robotic explorers. In order for such rover missions to be successful, they must carry instruments capable of i...