objective(s): this study aimed to compare the diagnostic values of 11c-choline and 18f-fluorodeoxyglucose (18f-fdg) positron emission tomography/computed tomography (pet/ct) in patients with cholangiocarcinoma (cca). methods: this prospective study was conducted on 10 patients (6 males and 4 females), aged 42-69 years, suspected of having cca based on ct or magnetic resonance imaging (mri) resu...

An 8-year-old girl was referred to us with fever, erythematous papules and painful subcutaneous nodules located over her extremities and bilateral arthritis of the ankles and knees. Laboratory findings revealed leucocytosis (13 410/mm) and elevated CRP concentration (1.4 mg/dl) and ESR (61 mm/h). MRI of the thighs revealed multiple high-signal nodular lesions throughout the subcutaneous tissue ...

Patient preparation for FDG PET studies is perhaps more critical and more complex than for any other commonly performed imaging procedure. We report a patient with normal blood glucose level prior to the execution of a PET study in which FDG uptake was virtually zero in internal organs and was very extense in large muscle groups. The patient recognizes ingestion several minutes before the test....

The Mediator complex governs gene expression by linking upstream signaling pathways with the basal transcriptional machinery. However, how individual Mediator subunits may function in different tissues remains to be investigated. Through skeletal muscle-specific deletion of the Mediator subunit MED13 in mice, we discovered a gene regulatory mechanism by which skeletal muscle modulates the respo...

Abstract B-cell lymphoblastic lymphoma (B-LBL) is an uncommon subtype of pediatric non-Hodgkin Lymphoma (NHL) which rarely involves the skin primarily. The positron emission tomography with 2-deoxy-2-[fluorine- 18] fluoro-D: -glucose integrated with computed tomography (18F-FDG PET/CT) scan findings of a 8-year-old boy with cutaneous B-LBL were presented. PET/CT scan demonstrated mild FDG up...

Introduction: Ursolic Acid (UA) is a lipophilic triterpenoid compound, found in large amounts in apple peel. Anabolic effects of UA on the skeletal muscle and the role of this tissue as a key regulator of systematic aging aroused this question in mind whether UA might amend skeletal muscle performances such as myoglobin expression and also whether it switches skeletal muscle fibers from glyc...

AIM The aim of this study was to study whether FDG was uniformly distributed throughout the skeleton and whether age and gender affected this biodistribution. MATERIAL AND METHODS A total of 158 patients were included in this retrospective study. None of the patients had received prior treatment that had affected the bone marrow and patients with bone metastases, trauma, benign and/or maligna...