BACKGROUND AND PURPOSE To define clinical manifestations and laboratory findings of adenovirus serotype 3 infections in children. METHODS A total of 499 children diagnosed with adenovirus infections based on throat virus cultures were treated in Chang Gung Children's Hospital from January 2004 to May 2005. Serotypes were determined in 197 strains, of which majority were serotype 3 (n = 147; 1...

Adenoviruses have been recognized as important causal pathogens of community-acquired diarrhea (CAD) among children, but their role in hospital-acquired diarrhea (HAD) is not well-understood. Hospitalized children with acute diarrhea and children who visited the outpatient department due to diarrhea were investigated from 2011 to 2012. Adenovirus was detected in stool specimens by PCR and furth...

Haemorrhagic septicemia (HS) caused by Pasteurella multocida (serotype B: 2) is an important disease of cattle and buffaloes in Asian sub-continent. Presently available vaccines for HS have their own limitations. Efforts have been made to develop better vaccine targeting outer membrane proteins and few of them have shown potential . Omp 87 protein has shown a protective potential against fowl c...

Currently, 90 different types of human adenoviruses (HAdV) are known, which have been classified into seven species from A to G and new adenovirus continue emerge. Antigenic diversity viruses inhibits the process creating universal vaccines causes development resistance direct-acting antiviral drugs. In addition rapid drug resistance, too narrow a range existing drugs significant number side ef...

In the present study characterisation has been done for six group I fowl adenoviruses (FAV) isolated from outbreaks of infectious hydropericardium (IHP) of chickens that occurred in different states/regions of India during the years 1994-98. These six viruses were identified as FAV serotype 4 by virus neutralisation and restriction endonuclease analyses. Antigenic analyses of the viruses reveal...

Human viral contamination in drinking and recreational waters poses health risks. The application of PCR-based molecular technology has advanced our knowledge of the occurrence and prevalence of human viruses in water; however, it has provided no information on viral viability and infectivity. Four human cell lines were compared for their sensitivity to different serotypes of human adenoviruses...

Vaccines delivering T cell immunogen HIVconsv vectored by plasmid DNA, non-replicating simian adenovirus and non-replicating modified vaccinia virus Ankara (MVA) are under clinical evaluation in phase I/IIa trials in UK, Europe, and Africa. While these vaccines aim to induce effector T cell responses specific for HIV-1, we here characterized the humoral responses induced by HIVconsv administrat...

In order to show the type and severity of gross and histopathologic lesions induce by vaccinal strain (serotype A1) of Pateurella mulocida, ten four-week-old SPF chickens were inoculated intramuscularly with 75 cfu of ( 0.5 ml of 10-7 dilution) bacterium. All birds died in less than 16 hours. No prominent gross lesions were observed in different organs. In microscopic examination, the most comm...