Amiodarone (AMD)-induced pulmonary toxicity (AIPT) is the most life-threatening side-effect of AMD treatment. N-Monodesethylamiodarone (DEA), an active metabolite of AMD, also exhibits cytotoxicity and tends to accumulate in the lung more intensively than AMD. In this study, we characterized the mechanism of DEA accumulation using A549 cells as a model of the alveolar epithelium. Typical ATP-de...

The selection of advanced manufacturing technologies (AMTs) is an essential yet complex decision that requires careful consideration various performance criteria. In real-world applications, there are cases observations difficult to measure precisely, represented as linguistic terms, or the data need be estimated. Since growth engineering sciences has been key reason for increased utilization A...

In this paper, we discuss the relationship between multi-attribute utility theory and DEA models without explicit inputs (DEA-WEI), including dual models and some theoretical analysis of DEA-WEI models. We then propose generic DEA-WEI models with quadratic utility terms. Finally, we provide illustrative examples to show that DEA-WEI with suitable quadratic utility terms are able to reflect some...

An important property of production functions is the concept return to scale (RTS) as found in the literature. There are two common variations RTS in data envelopment analysis (DEA) used, constant return to scale (CRS) and variation return to scale (VRS). The envelopment surface in BCC model is VRS and this is the result of the presence of the convexity constraint in the dual model and, equival...

Diethanolamine (DEA) is a common ingredient of personal care products. Dermal administration of DEA diminishes hepatic stores of the essential nutrient choline and alters brain development. We previously reported that 80 mg/kg/day of DEA during pregnancy in mice reduced neurogenesis and increased apoptosis in the fetal hippocampus. This study was designed to establish the dose-response relation...

Co-firing biomass plants are of extensive demand due to utilization of both agricultural residues (main) and natural gas (stand-by). Researchers have shown that one strategic decision in establishment of agricultural residues based plants, is location optimization problem. Moreover, mismatch between agricultural lands and biomass plants can lead to high transportation costs and related carbon d...

The data envelopment analytical hierarchy process (DEAHP) is a type of the analytical hierarchy process (AHP), which used the concept of data envelopment analysis (DEA) for generating LW from the judgment matrices and aggregating them to be final weight (FW) in AHP. In general, the judgment scales in AHP is built based on decision maker. It is unrealistic to expect that the decision maker has c...