Histopathology is crucial to diagnosis of cancer, yet its interpretation is tedious and challenging. To facilitate this procedure, content-based image retrieval methods have been developed as case-based reasoning tools. Especially, with the rapid growth of digital histopathology, hashing-based retrieval approaches are gaining popularity due to their exceptional efficiency and scalability. Never...

BACKGROUND High-grade transformation or dedifferentiation in carcinoma is progression of a low-grade malignant neoplasm to a high-grade carcinoma or poorly differentiated adenocarcinoma. This is rarely observed in adenoid cystic carcinoma of the salivary glands. CASE REPORT A 39 year-old woman presented with a painless mass at the left submandibulary region that had been growing slowly for 5 ...

Sixty male patients of leprosy (mean age = 27.2 +/- 5.04 years) selected at random, were studied for gonadal involvement and therapeutic efficacy of two indigenous drugs. Of these 34 were married, with the mean duration of illness 4.17 +/- 3.27 years. Only those with lepromatous and dimorphous leprosy developed testicular and epididymal changes. Testicular pain and/or swelling (lepromatous = 62...

BACKGROUND Traditionally, increased pericardial thickness has been considered an essential diagnostic feature of constrictive pericarditis. Although constriction with a normal-thickness pericardium has been demonstrated clinically by noninvasive imaging, the details of clinicopathological correlates have not been described. METHODS AND RESULTS A total of 143 patients with proven constriction ...

Oral lichen planus (OLP) and oral lichenoid lesions (OLL) are clinically and histologically similar lesions but their treatment planning and prognosis are different. The review of the literature indicates numerous criteria to distinguish these two lesions; however there is a lot of inconsistency. Thus, the aim of this study was to determine the correlation of histopathology and clinical OLP and...

BACKGROUND Dermoscopy is an important tool for the diagnosis of benign and malignant melanocytic diseases. Recently, this method has also been found to be extremely useful in the diagnosis and follow-up of alopecias. OBJECTIVE The objective of this study was to describe dermoscopic findings in patients with clinical and histopathological characteristics of cicatricial alopecia. METHODS A de...

oral lichen planus is diagnosed according to clinical and histopathological characteristics.some times all of the classical  histopathological features can not be seen.in some articles the presence of mast cells have been noted below the epithelium of oral lichen planus patients.the following study was done to evaluate the number of mast cells in the histopathological sections of 20 oral lichen...

Sir, Epidermotropic metastasis is an uncommon histopathological feature characterized by pagetoid spread of neoplastic cells in the epidermis. This special type of metastasis has been reported in several types of metastatic neoplasms, including malignant melanoma (1), eccrine porocarcinoma (2), squamous cell carcinoma (3), colon adenocarcinoma (4) and breast carcinoma (4, 5). On the other hand,...