Yeast cells mutated in YRB2, which encodes a nuclear protein with similarity to other Ran-binding proteins, fail to export nuclear export signal (NES)-containing proteins including HIV Rev out of the nucleus. Unlike Xpo1p/Crm1p/exportin, an NES receptor, Yrb2p does not shuttle between the nucleus and the cytoplasm but instead remains inside the nucleus. However, by both biochemical and genetic ...

The costs of additive manufactured parts often seem too high in comparison to those of traditionally manufactured parts, as the information about major cost drivers, especially for additive manufactured metal parts, is weak. Therefore, a lifecycle analysis of additive manufactured parts is needed to understand and rate the cost drivers that act as the largest contributors to unit costs, and to ...

iran's economy dependence on oil revenues has caused some impacts in the form of commodity price fluctuations on current revenues. accordingly, in the past few years especially in the second development plan, the government included encouragements and reduced the country's dependence on oil revenues in its agenda. agricultural export, especially livestock and poultry export has a proper status ...

abstract export of nonoil goods in economic activities is so important and its effect on economic and comparative growth is undeniable. so, emphasize on agricultural sector and development of export in this sector prepares good conditions, for iran, to be present at international markets relying its advantages. the study tries to recognize necessary policies to enhance agricultural export poten...

The rapid world economic growth have stimulated the businesses towards involvement in international marketplaces due to their low business risks, low commitment of resources and high flexibility. However, the evidence indicates barriers to export are thought to vary across different stages of internationalization. Therefore, this empirical study was carried out to explore export barriers of agr...

BACKGROUND Little research has been done to examine whether smokers switch to illegal or roll-your-own (RYO) cigarettes in response to a change in their relative price. OBJECTIVE This paper explores how relative prices between three cigarette forms (manufactured legal, manufactured illegal and RYO cigarettes) are associated with the choice of one form over another after controlling for covari...

Rodent cells are notable for their inability to support normal assembly of HIV particles. In this report, we address possible causes for this defect by considering the hypothesis that mRNA-associated events occurring in the nucleus can regulate the activity of their encoded proteins in the cytoplasm. We show that altering the RNA nuclear export element used by HIV gag-pol mRNA from the Rev resp...