objective(s): to explore the correlation between expression patterns and functions of mir-383 and ldha in hepatocellular cancer (hcc). materials and methods: we detected the expression of mir-383 and ldha in 30 hcc tissues and their matched adjacent normal tissues using qrt-pcr. then we performed mtt assay, foci formation assay, transwell migration assay, glucose uptake assay and lactate produc...

MicroRNAs (miRNAs) are short non-coding RNAs that regulate the expression of protein-coding genes by partially binding to specific target sites of mRNAs. miRNAs perform important functions in complicated cellular biological processes and their abnormal expression is involved in various disorders, including cancer. Among the miRNAs, differential expression of miR-139-5p serves a significant role...

We describe a large-scale and complete experiment aiming at validating the hypothesis that the popularity of music titles can be learnt using global acoustic or human features. We use a 32.000 title database with 632 manually-entered attributes per titles including 3 related to the popularity of the title. We design an experiment with two different audio feature sets, as well as the set of all ...

In this paper we present a novel extended formulation for the line planning problem that is based on what we call “configurations” of lines and frequencies. Configurations account for all possible options to provide a required transportation capacity on an infrastructure edge. The proposed configuration model is strong in the sense that it implies several facet-defining inequalities for the sta...

Determining that miRNAs play a role in breast cancer pathogenesis suggests it may be useful the diagnosis and treatment of cancer. In this study, 39 patients with invasive were diagnosed serum levels 20 miRNAs(miR-105, miR-21, miR-141, miR-200a, miR-200b, miR-200c, miR-203, miR-210, miR-375, miR-34a, miR-133a, miR-155, miR-139-5p, miR-143, miR-145, miR-365, miR-299-5p, miR-411, miR-452, miR-17)...

The continued growth of MIR is motivating more complex annotation data, consisting of richer information, multiple annotations for a given task, and multiple tasks for a given music signal. In this work, we propose JAMS, a JSON-based music annotation format capable of addressing the evolving research requirements of the community, based on the three core principles of simplicity, structure and ...

Microblogging services, such as Twitter, have risen enormously in popularity during the past years. Despite their popularity, such services have never been analyzed for MIR purposes, to the best of our knowledge. We hence present first investigations of the usability of music artist-related microblogging posts to perform artist labeling and similarity estimation tasks. To this end, we look into...