Purpose-The purpose of this paper is to propose a robust ‘observation’ procedure drawn from the social science research literature for adoption in a Lean Six Sigma project setting. A case study illustrates the application of the proposed observation procedure in a Lean Six Sigma project undertaken in a European airport to improve process speed and reduce variability. Design/methodology/approach...

  Purpose: Despite discovering new antibiotics, mortality due to septic shock has remained high.   This research has examined the effect of selenase in patients with septic shock admitted to the   intensive care unit (ICU) of a hospital in Tehran.   Materials and Methods: This double-blind clinical trial was done on 80 participants (40 case   and 40 control) who were admitted to the ICU with se...

Inventory models in which the demand rate dependents on the stock- dependent are based on the common real- life observation that greater product availability tends to stimulate more sales. In this study we develop an inventory model to determine an optimal ordering policy for quantity dependent demand rate and time dependent holding cost items with delay in payments permitted by the supplier un...

Outcomes in RCT's of antipsychotic medications are often examined using last observation carried forward (LOCF) and mixed effect models (MMRM), these ignore meaning of non-completion and thus rely on questionable assumptions. We tested an approach that combines into a single statistic, the drug effect in those who complete trial and proportion of patients in each treatment group who complete tr...

A measles epidemic occurred in Romania with 32,915 cases and 21 deaths reported between November 1996 and June 1998, despite high vaccination coverage since the early 1980s. Most cases were unvaccinated children aged <2 years and vaccinated school-aged children. A case-control study among preschool children and a cohort study among primary-school children were conducted to estimate effectivenes...