PURPOSE We describe a patient who presented with unilateral paresthesia after acute isolated infarct of the splenium. CASE REPORT A 74-year-old woman presented with acute onset of right sided numbness and tingling. MR imaging of the brain showed hypointensity on T1-weighted images and on apparent diffusion coefficient maps, and hyperintensity on T2-weighted and on diffusion-weighted images in...

Assessment of the peripapillary nerve fiber layer and macular thickness can be determined in ophthalmology using optical coherence tomography (OCT). Decreased nerve fiber layer thickness and macular ganglion cell thickness in optic nerve ischemia have been correlated with visual field loss. OCT allows deep optic nerve head evaluation which helps understand pathophysiology of diseases.  Furtherm...

FRIEDREICH 'S ATAXIA is one of the rare heritable spinocerebellar degenerations. The spinocerebellar tracts, dorsal columns, pyramidal tracts, and, to a lesser extent, the cerebellum and medulla are involved. The disorder is usually manifest before adolescence and is generally characterized by incoordination of limb movements, dysarthria, nystagmus, diminished or absent deep tendon reflexes, Ba...

background: friedreich ataxia (frda) is an autosomal recessive disorder caused by guanine-adenine-adenine (gaa) triplet expansions in the fxn gene. its product, frataxin, which severely reduces in frda patients, leads to oxidative damage in mitochondria. the purpose of this study was to evaluate the triple nucleotide repeated expansions in iranian frda patients and to elucidate distinguishable ...

Introduction: Demyelination is one of the main causes of neurological disability. It is the end product of numerous pathological processes, multiple sclerosis (MS) being the most common cause. More than 70% of the MS patients suffer from optic disturbances. This disease commonly affects the optic pathway, particularly the optic nerves and chiasm. Several attempts have been made to produce a ...

  Background :There is not any data available about the effect of high bar pressure condition on intracranial pressure. In this study, the effect of diving on the optic nerve and sheath diameters as non-invasive markers of intracranial pressure has been investigated.   Methods : Twenty professional male divers from twenty one volunteers were chosen for this cross-sectional study. Only one perso...

Purpose. Evaluate the diagnostic significance of quantitative determination T- and B-cell receptor DNA ring fragments in peripheral blood patients for diagnosis ataxia-teleangiectasia. Materials methods. The subjects study were samples from 14 diagnosed with ataxia-teleangiectasia aged 4.9 (1.6; 14.4) years mutations ATM gene 40 healthy children 11.0 (6.7; 14.8) years. Results discussion. Patie...

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