conclusions we found ccd and rsm very effective in optimizing hib culture conditions, and hib biomass production was greatly influenced by ph and incubation temperature. therefore, optimization of the growth factors to maximize hib production can lead to 1) an increase in bacterial biomass and prp productions, 2) lower vaccine prices, 3) vaccination of more susceptible populations, and 4) lower...

The impetus of this study is to investigate the chaotic behavior of a size-dependent nano-beam with double-sided electrostatic actuation, incorporating surface energy effect and intermolecular interactions. The geometrically nonlinear beam model is based on Euler-Bernoulli beam assumption. The influence of the small-scale and the surface energy effect are modeled by implementing the consistent ...

Recent papers in the concept of Supply Chain Network Design (SCND) have seen a rapid development in applying the stochastic models to get closer to real-world applications. Regaring the special characteristics of each product, the stracture of SCND varies. In tire industry, the recycling and remanufacturing of scraped tires lead to design a closed-loop supply chain. This paper proposes a two-st...

This paper develops a single-vendor single-retailer supply chain for multi-product. The proposed model is based on Vendor Managed Inventory (VMI) approach and vendor uses the retailer's data for better decision making. Number of orders and available capital are the constraints of the model. In this system, shortages are backordered; therefore, the vendor’s warehouse capacity is another limitati...

in this paper, the modified euler-bernoulli beam model is presented to examine the influence of surface elasticity and residual surface tension on the critical force of axial buckling of nanotubes in the presence of rotary inertia. an explicit solution is derived for the buckling loads of microscaled euler beams considering surface effects. the size-dependent buckling behavior of the nanotube d...

this paper develops a single-vendor single-retailer supply chain for multi-product. the proposed model is based on vendor managed inventory (vmi) approach and vendor uses the retailer's data for better decision making. number of orders and available capital are the constraints of the model. in this system, shortages are backordered; therefore, the vendor’s warehouse capacity is another limitati...

functionally graded aluminium/zirconia metal matrix composite was fabricated using stir casting technique followed by horizontal centrifugal casting process and a hollow cylindrical functionally graded composite (150 x 150 x 16 mm) was obtained with centrifuging speed of 1200 rpm. the microstructural evaluation and hardness test was carried out on the outer and inner surface of the functionally...

angelica essential oil (ao), a major pharmacologically active component of angelica sinensis (oliv.) diels, possesses hemogenesis, analgesic activities and sedative effect. the application of ao in pharmaceutical systems had been limited because of its low oxidative stability. the ao-loaded gelatin-chitosan microcapsules with prevention from oxidation were developed and optimized using response...