background : identifying the sources of variation in qtc measurements is important for preventing arrhythmias during and after hemodialysis. the present study was designed to determine the correlation between the type of hemodialysis buffer and the changes in qtc interval in patients on chronic hemodialysis.   methods: fifty-nine patients on chronic hemodialysis who referred in winter 2007 to h...

Pruritus is one of the most debilitating symptoms for patients with epidermolysis bullosa (EB). This study aimed to assess burden itch and address its dimensions across EB. Forty-six EB were recruited from Saudi registry participate. All participants completed Leuven Itch Scale. The sample included 5 simplex (EBS), 3 junctional (JEB), 34 dystrophic (DEB), 4 had unknown type. Overall, 97.8% repo...

The effects and mechanisms of action of diepoxybutane (DEB) and mitomycin C (MMC) were investigated on sea urchin embryogenesis, (Sphaerechinus granularis and Paracentrotus lividus). DEB- and MMC-induced toxicity was evaluated by means of selected end-points, including developmental defects, cytogenetic abnormalities and alterations in the redox status [oxygen-dependent toxicity, Mn-superoxide ...

Objective Hyponatremia is frequently observed in patients with decompensated liver cirrhosis and it is also related to a poor prognosis. The vasopressin V2-receptor antagonist tolvaptan is used to treat cirrhotic patients with ascites and increases the serum sodium (Na) level. In this study, we investigated (i) whether or not correction of the Na level improves the prognosis of cirrhotic patien...

The ratiometric indicators 2 0,7 0-bis-(2-carboxyethyl)-5-(and-6)-carboxyfluorescein and Fura-2 were employed to examine, respectively, intracellular pH (pHi) and calcium ([Ca]i) changes evoked by anoxia in cultured postnatal rat hippocampal neurons at 378C. Under both HCO3 /CO2and HEPES-buffered conditions, 3-, 5or 10-min anoxia induced a triphasic change in pHi consisting of an initial fall i...

Dystrophic epidermolysis bullosa (DEB) is a hereditary skin disorder characterized by traumainduced blistering. It is caused by mutations in the collagen VII gene, COL7A1, which consists of 118 small exons. Molecular diagnostics in DEB remain complex due to the gene structure, large variety of mutations, high rate of novel mutations, and the heterogeneity of phenotypes. Using a highly sensitive...

Background Drug eluting balloon (DEB) is a new therapeutic option for treatment of obstructive coronary lesions in percutaneous coronary intervention (PCI). There is limited data on the safety and efficacy of DEB in Asian patients in contemporary clinical registries. We evaluated the clinical efficacy and safety of SeQuent Please paclitaxel-eluting balloon in our cohort of South-East Asian pati...

In the paper, we introduce new dictionary management interface for design, preparation and presentation of generic electronic XML dictionaries using the DEB (Dictionary Editing and Browsing) development platform. The DEB platform provides a strict client-server environment for general dictionary writing systems. So far several successful NLP tools have been implemented on this platform, one of ...

A rise in cytosolic Ca(2+) concentration ([Ca(2+)](cyt)) in pulmonary artery smooth muscle cells (PASMC) is a trigger for pulmonary vasoconstriction and a stimulus for PASMC proliferation and migration. Multiple mechanisms are involved in regulating [Ca(2+)](cyt) in human PASMC. The resting [Ca(2+)](cyt) and Ca(2+) entry are both increased in PASMC from patients with idiopathic pulmonary arteri...