E-learning may provide a lot of useful features in a wide range of learning and teaching situations. However, the provision of static learning material will not meet the requirements of the users. We believe that well-tailored, highly personalized learning sessions are needed. Regarding to this background, the research project AdeLE (Adaptive e-Learning with Eye-Tracking) aims to develop and im...

Silicates are well known for their bioactivity, here we are reporting the bioactivity of diopside (CaMgSi2O6) synthesized by sol-gel combustion process by using citric acid and succinic acid as a mixed fuel. The phase formation of the prepared sample was confirmed by powder X-Ray Diffraction. In-vitro bioactivity of the diopside in conjugation with biopolymer chitin in various proportions were ...

In the present study, a nanoporous metal organic framework (MOF) based on iron metal and amino terephthalate ligand MIL-101-NH2-Fe has been used as a carrier for loading and in vitro release of 5-flurouracil (5-FU) anticancer drug. The 5-FU drug loaded MOF was 13 wt % by using thermogravimetric analysis (TGA). The 5-FU release was monitored under physiological condition at 37°C, pH 7.4 in simul...

Significant research has been devoted to the development of hydroxyapatite (HA) as a coating material for metallic biomaterials used in bioimplants where the biocompatibility is provided by HA while the mechanical properties of the implant are confirmed by the metallic substrates. The in vitro tests of these coatings have conducted by soaking in simulated body fluid (SBF) solutions to evaluate ...

MBF and SBF transcription factors regulate a large family of coordinately expressed G1/S genes required for early cell-cycle functions including DNA replication and repair. SBF is inactivated upon S-phase entry by Clb/CDK whereas MBF targets are repressed by the co-repressor, Nrm1. Using genome-wide expression analysis of cells treated with methyl methane sulfonate (MMS), hydroxyurea (HU) or ca...

An injectable material consisting of calcium sulphate mixed with hydroxyapatite was investigated as a possible alternative to autograft in the restoration of bone defects. The material was studied both in vitro in simulated body fluid (SBF) and in vivo when implanted in rat muscles and into the proximal tibiae of rabbits. Variation in the strength and weight of the material during ageing in SBF...

Abstract. Modeling applications and architectures at various levels of abstraction is becoming more and more an accepted approach in embedded system design. When looking at the modeling of applications in the domain of video, audio, and graphics applications, we notice that they exhibit a high degree of task parallelism and operate on streams of data. Models that we can use to specify such stre...

The hydroxyapatite (HA) formation on the DNA molecules in SBF was examined. After immersion for four weeks in SBF at 36.5 °C, the HA crystallites of ~1-14 μm in diameter grew on the surface of DNA molecules. Various morphologies were successfully observed through scanning electron microscopy analysis. The Ca/P mol ratio (1.1-1.5) in HA was estimated by energy dispersive X-ray analysis. Original...

Introduction: In recent study both endothelium-dependent and endothelium-independent mechanisms have been reported for the action of β-adrenoceptor. The aim of this study was to investigate on the role of nitric oxide (NO) and cyclic guanosin monophosphate (cGMP) in vasodilation mechanisms of β2-adrenoceptors (β2-AR) in rat skin vessels. Methods: All drugs were injected subcutaneous into p...

The Surface Brightness Fluctuation method has been shown to be a powerful distance indicator for dwarf elliptical galaxies to very low surface brightness levels. It is applicable to stellar systems that are out of reach for classical indicators requiring resolved stellar populations such as the tip magnitude of the red giant branch. I briefly discuss a few results from recent SBF studies of dEs...