نتایج جستجو برای: 52 and 627
تعداد نتایج: 16839895 فیلتر نتایج به سال:
To determine the role of endothelin-1 (ET-1) and its receptors in salt-sensitive hypertension induced by sensory nerve degeneration, selective ET(A) antagonist (ABT-627) and ET(B) antagonist (A-192621) were used. Newborn Wistar rats were given vehicle or 50 mg/kg capsaicin subcutaneously on the first and second days of life. After the weaning period, male rats were divided into eight groups, an...
The endothelin A receptor (ET(A)R) autocrine pathway is overexpressed in many malignancies, including ovarian carcinoma. In this tumor, engagement of ET(A)R triggers tumor growth, survival, neoangiogenesis, and invasion. To evaluate whether ET(A)R represents a new target in cancer treatment, we examine in vitro and in vivo the effect of the selective ET(A)R antagonist ABT-627 (atrasentan), a sm...
The RNA genome of influenza A viruses is transcribed and replicated by the viral RNA-dependent RNA polymerase, composed of the subunits PA, PB1, and PB2. High-resolution structural data revealed that the polymerase assembles into a central polymerase core and several auxiliary highly flexible, protruding domains. The auxiliary PB2 cap-binding and the PA endonuclease domains are both involved in...
acknowledgements i wish to express my gratitude to all those who have helped me in preparing this thesis. i would like to express my deep gratitude to my respected advisor dr. kourosh akef, whose advice and comments helped me in the early stages of the research and throughout the writing process. i would also like to express my gratitude to dr. hajar khanmohammad whose invaluable guidance he...
the following null hypothesis was proposed: there is no significant difference between the efl students listening comprehension development receiving pictorial cues and those receiving no cuse. to test the null hypothesis, 52 male and femal freshmen students of medicine studing at iran university of medical scinces were randomly selected from a total population of 72 students. to ensure that th...
Cytochrome P450 enzyme CYP3A4 is an important drug-metabolizing enzyme, and high levels of tumoral expression of CYP3A4 are linked to drug resistance. We investigated the function of vitamin D-regulated miR-627 in intratumoral CYP3A4 suppression and its role in enhancing the efficacy of chemotherapy. We found that miR-627 targets CYP3A4 and suppresses CYP3A4 expression in colon cancer cell line...
Im Rahmen des seit Januar 2003 von der Deutschen Forschungsgemeinschaft geförderten Sonderforschungsbereichs 627 Umgebungsmodelle für mobile kontextbezogene Systeme 1 werden an der Universität Stuttgart grundlegende Forschungsarbeiten zur Erstellung, Nutzung, Aktualisierung und Ausgestaltung digitaler Weltmodelle und zu deren Nutzung in kontextbezogenen Informationssystemen durchgeführt. Forsch...
to teach english adequately, qualified teachers are needed. unfortunately, there are still teachers who are teaching english without an academic degree in tefl. it is necessary for teachers to have a major in english to have subject knowledge, but it is not sufficient. teachers need to have an understanding of the social, cultural, moral, ethical, and pedagogical issues of education and practic...
1. Tans, S . J., Verschueren, R. M. & Dekker, C. Nature 393, 49–52 (1998). 2. Martel, R., Schmidt, T., Shea, H. R., Hertel, T. & Avouris, Ph. Appl. Phys. Lett. 73, 2447–2449 (1998). 3. Antonov, R. D. & Johnson, A. T. Phys. Rev. Lett. 83, 3274–3276 (1999). 4. Soh, H. T. et al. Appl. Phys. Lett. 75, 627–629 (1999). 5. Yao, Z., Postma, H. W. Ch., Balents, L. & Dekker, C. Nature 402, 273–276 (1999)...
نمودار تعداد نتایج جستجو در هر سال
با کلیک روی نمودار نتایج را به سال انتشار فیلتر کنید