Family studies of exceptional longevity can potentially identify genetic and other factors contributing to long life and healthy aging. Although such studies seek families that are exceptionally long lived, they also need living members who can provide DNA and phenotype information. On the basis of these considerations, the authors developed a metric to rank families for selection into a family...

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The idea that aging is a purposeful, programmed series of events is intuitively appealing based on its many conserved aspects and the demonstrated feasibility of modifying life span by manipulating single genes or pathways. Yet, the case for a nonadaptive basis of aging is strong and now all but generally accepted in the field. Here, we briefly review why the case for programmed aging is weak, ...

The idea that aging is a purposeful, programmed series of events is intuitively appealing based on its many conserved aspects and the demonstrated feasibility of modifying life span by manipulating single genes or pathways. Yet, the case for a nonadaptive basis of aging is strong and now all but generally accepted in the field. Here, we briefly review why the case for programmed aging is weak, ...

The genetic analysis of the yeast replicative life span has revealed the importance of metabolic control and resistance to stress. It has also illuminated the pivotal role in determining longevity that the RAS genes play by the maintenance of homeostasis. This role appears to be performed by the coordination of a variety of cellular processes. Metabolic control seems to occupy a central positio...

Alstroemeria is one of the most popular cut flowers in European Union owing to its postharvest longevity and broad color spectra. Nevertheless, premature wilting decreases the aesthetic value of flowering branches even before the opening of the secondary florets in the fluorescence. The present study evaluated different biochemical and morphological traits of Alstroemeria cut ...

Background and Aim: Restoration of endodontically treated teeth is one of the most important and challenging topics in restorative dentistry. Longevity of such restorations is an essential factor in treatment planning. Amalgam build-up is a conservative method for restoration of endodontically treated teeth. Therefore, this study aimed to assess the longevity of this type of restoration in endo...

Climate change affects the abundance, distribution and activity of natural enemies that are important for suppressing herbivore crop pests. Moreover, higher mean temperatures and increased frequency of climatic extremes are expected to induce different responses across trophic levels, potentially disrupting predator-prey interactions. Using field observations, we examined the response of an aph...