In the present study, the effect of NBM lesion on the temporal characteristics of response integration evoked by multiple whisker stimulations in the barrel cortex of rats was studied. Nucleus basalis of Meynert (NBM) projects to widespread areas of the cortex and provides the major cholinergic input (80%) to the cerebral cortex. In this study we examined the effects of NBM lesion on the respon...

there are some conflicts about constancy of conduction velocity (cv) in a given tract of nervous system. by recording excitatory postsynaptic currents (epsc) in layer iv of the somatosensory cortex we tried to clear changes in cv of thalamocortical tract of mice aged 3 to 50 days old. field potentials and epsc were recorded in the layer iv by stimulation of ventrobasal nucleus of thalamus (vb) ...

In the rodent vibrissal system, active sensation and sensorimotor integration are mediated in part by connections between barrel cortex and vibrissal motor cortex. Little is known about how these structures interact at the level of neurons. We used Channelrhodopsin-2 (ChR2) expression, combined with anterograde and retrograde labeling, to map connections between barrel cortex and pyramidal neur...

Introduction: Barrel cortex of rats is a part of somatosensory cortex, which receives information from facial whiskers. Vibrisectomy by sensory deprivation leads to some changes in the barrel cortex, which have been known as experience dependent plasticity. On the other hand, Norepinephrine (NE) and locus coeruleus, which is the main source of NE, influenced response properties of cortical bar...

Whisker deflection is an effective conditioned stimulus (CS) for trace eyeblink conditioning that has been shown to induce a learning-specific expansion of whisker-related cortical barrels, suggesting that memory storage for an aspect of the trace association resides in barrel cortex. To examine the role of the barrel cortex in acquisition and retrieval of trace eyeblink associations, the barre...

change in transmitting time of impulses along axons is traditionally attributed to two parameters: the myelin formation and the diameter of neurite, both rising during the postnatal development. in the previous study, we showed that conduction velocity of the fibers projecting from the thalamus to the layer iv of the somatosensory (barrel) cortex increases as a function of age. however, the con...

In rats, navigating through an environment requires continuous information about objects near the head. Sensory information such as object location and surface texture are encoded by spike firing patterns of single neurons within rat barrel cortex. Although there are many studies using single-unit electrophysiology, much less is known regarding the spatiotemporal pattern of activity of populati...

In the barrel cortex, several features of single-whisker stimuli are organized in functional maps. The barrel cortex also encodes spatio-temporal correlation patterns of multi-whisker inputs, but so far the cortical mapping of neurons tuned to such input statistics is unknown. Here we report that layer 2/3 of the rat barrel cortex contains an additional functional map based on neuronal tuning t...